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- SparkJade
- SJ-MX3265A
- 2026年06月01日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Pefloxacin mesylate
- 库存：
现货
- CAS号：
70458-95-6
- 规格：
25 mg/50 mg/100 mg/200 mg/500 mg/1 g
| 规格： | 25 mg | 产品价格： | ￥100.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥140.0 |
| 规格： | 100 mg | 产品价格： | ￥180.0 |
| 规格： | 200 mg | 产品价格： | ￥260.0 |
| 规格： | 500 mg | 产品价格： | ￥420.0 |
| 规格： | 1 g | 产品价格： | ￥640.0 |
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文献和实验Detection of BCR-ABL Mutations and Resistance to Imatinib Mesylate
The major mechanism of imatinib resistance for patients with chronic myeloid leukemia (CML) is clonal expansion of leukemic cells with mutations in the Bcr-Abl fusion tyrosine kinase that reduce the capacity of imatinib to inhibit kinase
-4 and C-5 centers ( 3 ). After formatron of the mesylate, from the recycled material the amine function is introduced through azrde displacement of the mesylate, followed by reduction ( 4 ) and protectron with the t -BOC group. Finally, the lactone
Inhibitors of Cellular Signaling Targets: Designs and Limitations
. Because of their central role in cellular signaling, as well as their primary role in disease progression, protein kinases are attractive therapeutic targets (2 ,3 ). Seven molecules targeting protein kinases, imatinib mesylate (Gleevec) and trastuzumab (Herceptin
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