DUSP2 Polyclonal antibody产品图
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DUSP2 Polyclonal antibody

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  • ¥300 - 3000
  • proteintech
  • 国内
  • 27327-1-AP
  • 2026年05月28日
  • WB, ELISA
  • Rabbit / IgG
  • human, mouse
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原:

      详询

    • 亚型:

      IgG

    • 形态:

      液体

    • 保存条件:

      -20℃

    • 克隆性:

      Polyclonal

    • 标记物:

      Unconjugated

    • 适应物种:

      human, mouse

    • 保质期:

      详询

    • 抗原来源:

      详询

    • 目录编号:

      详询

    • 级别:

      科研级

    • 库存:

      现货

    • 供应商:

      上海艾科斯生物科技有限公司

    • 宿主:

      Rabbit / IgG

    • 应用范围:

      WB, ELISA

    • 浓度:

      400 ug/ml

    • 靶点:

      DUSP2

    • 抗体英文名:

      DUSP2

    • 抗体名:

      DUSP2

    • 规格:

      50 μL/100 μL/150 μL

    【产品概述】
    本产品为DUSP2 Polyclonal antibody(货号:27327-1-AP),由Rabbit / IgG宿主制备。该抗体属于Polyclonal抗体,可识别human, mouse来源的靶蛋白,经测试适用于WB, ELISA等实验应用。产品形式为Liquid,偶联物类型为Unconjugated。

    【背景介绍】
    DUSP2 belongs to the sub-family of nuclear specific DUSPs that includes DUSP1, 4 and 5. DUSP2 is highly expressed in immune cells, in particular, of patients with inflammatory arthritis, such as in rheumatoid arthritis (RA), and Dusp2 knockout mice present a significant reduction in inflammatory responses. It has been demonstrated that DUSP2 is a downstream target of the tumor suppressor p53 that is required for the cellular response to oxidative stress. DUSP2 is also involved in transcription factor E2F1-mediated apoptotic signaling. Like other members of the DUSP family, DUSP2 interacts with MAPKs; However, the target protein for its phosphatase activity is controversial.

    【产品特点】
    本抗体采用Antigen affinity purification方式纯化,确保了高特异性和批次间一致性。观测分子量约为34 kDa。推荐稀释比:WB: WB : 1:500-1:2000。Western Blot检测阳性对照组织/细胞为A549 cells, HeLa cells。储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.。Proteintech抗体经过严格的质量验证流程,确保研究人员获得可重复且可靠的实验结果。

    【产品信息】
    GenBank蛋白编号:BC007771;基因名称:DUSP2;Gene ID (NCBI):1844;UNIPROT ID:Q05923;RRID:AB_2880845;别名包括:dual specificity phosphatase 2, DUSP2, PAC 1, PAC1;免疫原为CatNo:Ag25380Product name: Recombinant human DUSP2 proteinSource:e coli.-derived, PET30aTag: 6*HisDomain: 1-314 aa ofBC007771Sequence: MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH种属同源性预测;储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.;产品形式为Liquid;纯化方式为Antigen affinity purification。

    产品细节图片1

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    图标文献和实验
    该产品被引用文献
    [1] Wang Y, Chen Y, Zhang L, et al. CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma[J]. Autophagy, 2024.
    [2] Li X, Wang H, Zhang J, et al. Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer[J]. Nature Communications, 2024.
    [3] Zhang Y, Liu H, Chen X, et al. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics[J]. Nature Cell Biology, 2024.
    [4] Yang F, Li M, Wang S, et al. A glycolytic shift in Schwann cells supports injured axons[J]. Nature Neuroscience, 2024.
    [5] Chen L, Zhao R, Wang H, et al. Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer[J]. Cell Metabolism, 2024.
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Construction of Polyclonal Antibody Libraries Using Phage Display

      Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified

    图标技术资料

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    文献支持
    DUSP2 Polyclonal antibody
    ¥300 - 3000