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PSMD4 Polyclonal antibody

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  • ¥300 - 3000
  • proteintech
  • 国内
  • 14899-1-AP
  • 2026年05月28日
  • WB, IHC, IF/ICC, FC (Intra), ELISA
  • Rabbit / IgG
  • human, mouse, rat
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      详询

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      -20℃

    • 克隆性

      Polyclonal

    • 标记物

      Unconjugated

    • 适应物种

      human, mouse, rat

    • 保质期

      详询

    • 抗原来源

      详询

    • 目录编号

      详询

    • 级别

      科研级

    • 库存

      现货

    • 供应商

      上海艾科斯生物科技有限公司

    • 宿主

      Rabbit / IgG

    • 应用范围

      WB, IHC, IF/ICC, FC (Intra), ELISA

    • 浓度

      400 ug/ml

    • 靶点

      PSMD4

    • 抗体英文名

      PSMD4

    • 抗体名

      PSMD4

    • 规格

      50 μL/100 μL/150 μL

    【产品概述】
    本产品为PSMD4 Polyclonal antibody(货号:14899-1-AP),由Rabbit / IgG宿主制备。该抗体属于Polyclonal抗体,可识别human, mouse, rat来源的靶蛋白,经测试适用于WB, IHC, IF/ICC, FC (Intra), ELISA等实验应用。产品形式为Liquid,偶联物类型为Unconjugated。

    【背景介绍】
    PSMD4, also named as MCB1, AF or ASF, belongs to the proteasome subunit S5A family. PSMD4 is a 50-kD subunit of the regulatory complex of the 26S proteasome. It binds and presumably selects ubiquitin-conjugates for destruction. PSMD4 displays selectivity for longer polyubiquitin chains. It modulates intestinal fluid secretion. PSMD4 is exposed on the sperm acrosomal surface, a notion that was further supported by the binding of non-cell permeant, biotinylated proteasomal inhibitor ZL3VS to the sperm acrosome. It is involved in the sperm-ZP penetration during fertilization. (PMID: 20526895) This antibody is specific to PSMD4.

    【产品特点】
    本抗体采用Antigen affinity purification方式纯化,确保了高特异性和批次间一致性。观测分子量约为50 kDa。推荐稀释比:WB: WB : 1:5000-1:50000;IHC: IHC : 1:50-1:500。Western Blot检测阳性对照组织/细胞为Jurkat cells, rat spleen tissue, K-562 cells, HeLa cells, NIH/3T3 cells, RAW264.7 cells, Raji cells。储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.。Proteintech抗体经过严格的质量验证流程,确保研究人员获得可重复且可靠的实验结果。

    【产品信息】
    GenBank蛋白编号:BC002365;基因名称:PSMD4;Gene ID (NCBI):5710;UNIPROT ID:P55036;RRID:AB_2170627;别名包括:26S proteasome non-ATPase regulatory subunit 4, AF, ASF, MCB1, Multiubiquitin chain-binding protein;免疫原为CatNo:Ag6691Product name: Recombinant human PSMD4 proteinSource:e coli.-derived, PGEX-4TTag: GSTDomain: 1-377 aa ofBC002365Sequence: MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATTGTEDSDDALLKMTISQQEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDG;储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.;产品形式为Liquid;纯化方式为Antigen affinity purification。

    产品细节图片1

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    图标文献和实验
    该产品被引用文献
    [1] Wang Y, Chen Y, Zhang L, et al. CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma[J]. Autophagy, 2024.
    [2] Li X, Wang H, Zhang J, et al. Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer[J]. Nature Communications, 2024.
    [3] Zhang Y, Liu H, Chen X, et al. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics[J]. Nature Cell Biology, 2024.
    [4] Yang F, Li M, Wang S, et al. A glycolytic shift in Schwann cells supports injured axons[J]. Nature Neuroscience, 2024.
    [5] Chen L, Zhao R, Wang H, et al. Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer[J]. Cell Metabolism, 2024.
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Construction of Polyclonal Antibody Libraries Using Phage Display

      Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified

    图标技术资料

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    文献支持
    PSMD4 Polyclonal antibody
    ¥300 - 3000