- ￥300 - 3000
- proteintech
- 国内
- 13295-1-AP
- 2026年05月27日
- WB, IHC, ELISA
- Rabbit / IgG
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
详询
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat
- 保质期：
详询
- 抗原来源：
详询
- 目录编号：
详询
- 供应商：
上海艾科斯生物科技有限公司
- 宿主：
Rabbit / IgG
- 应用范围：
WB, IHC, ELISA
- 浓度：
400 ug/ml
- 靶点：
Cyclin A1
- 抗体英文名：
Cyclin A1
- 抗体名：
Cyclin A1
- 规格：
50 μL/100 μL/150 μL
【产品概述】
本产品为Cyclin A1 Polyclonal antibody（货号：13295-1-AP），由Rabbit / IgG宿主制备。该抗体属于Polyclonal抗体，可识别human, mouse, rat来源的靶蛋白，经测试适用于WB, IHC, ELISA等实验应用。产品形式为Liquid，偶联物类型为Unconjugated。
【背景介绍】
CCNA1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNA1 binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. CCNA1 was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. In general, the expression of CCNA1 is tissue-specific and high CCNA1 expression is limited to testis; besides, lower levels of CCNA1 expression are also observed in other human cell lines and in healthy brain. Currently, CCNA1 expression has been illustrated to be downregulated in various tumors, including head and neck squamous-cell cancer (HNSCC) and nasopharyngeal carcinoma; and the promoter of the CCNA1 gene is found to be frequently methylated in colon cancer and HNSCC.
【产品特点】
本抗体采用Antigen affinity purification方式纯化，确保了高特异性和批次间一致性。观测分子量约为52 kDa。推荐稀释比：WB: WB : 1:500-1:1000；IHC: IHC : 1:500-1:2000。Western Blot检测阳性对照组织/细胞为mouse testis tissue, rat testis tissue。储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.，储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.。Proteintech抗体经过严格的质量验证流程，确保研究人员获得可重复且可靠的实验结果。
【产品信息】
GenBank蛋白编号：BC036346；基因名称：Cyclin A1；Gene ID (NCBI)：8900；UNIPROT ID：P78396；RRID：AB_2071993；别名包括：CCNA1, cyclin A1；免疫原为CatNo:Ag4005Product name: Recombinant human CCNA1 proteinSource:e coli.-derived, PGEX-4TTag: GSTDomain: 166-465 aa ofBC036346Sequence: GTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ种属同源性预测；储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.，储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.；产品形式为Liquid；纯化方式为Antigen affinity purification。
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
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