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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
3 months at -20°C
- 英文名:
NGF R, Human
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 规格:
10μg/50μg/1mg
| 规格: | 10μg | 产品价格: | ¥400.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥1100.0 |
| 规格: | 1mg | 产品价格: | ¥15200.0 |
| Species | Human | |
| Protein Construction |
|
|
| Purity | > 95% as analyzed by SDS-PAGE | |
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
| Biological Activity | ED50 < 0.4 μg /ml, measured in a neutrolization assay using TF-1 cells in the presence of 10.0 ng/ml human b-NGF. | |
| Expression System | HEK 293 | |
| Apparent Molecular Weight | 32~60 kDa, on SDS-PAGE under reducing conditions. | |
| Formulation | Lyophilized after extensive dialysis against PBS. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for 6 months at lower than -70°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
| Target Background | NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist. |
| Synonyms | Gp80-LNGFR; p75 ICD; CD271; TNFRSF16 |
产品特点:
1. 【人源天然序列】采用人源 IL-21 天然氨基酸序列,无突变,与体内天然蛋白结构完全一致,可特异性结合 IL-21 受体2. 【高活性高特异性】可高效结合 IL-21 受体,ED₅₀ < 100 ng/mL(受体结合实验),可被 IL-21 特异性抗体识别,适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.2 EU/μg(LAL 法),适配免疫细胞培养、体内免疫实验等敏感场景需求4. 【易纯化检测】哺乳动物细胞表达,可通过亲和层析快速纯化,也可通过 IL-21 特异性抗体进行检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 IL-21 蛋白结构与功能研究、免疫调控与炎症机制研究、肿瘤免疫治疗研究、细胞培养添加剂、药物筛选、抗体研发等
IL-21, 白细胞介素 21, 人源,人,重组蛋白,重组,高活性,高纯度,低内毒素,细胞培养,免疫细胞,科研实验,哺乳动物细胞表达,Human,IL-21,Recombinant protein,IL-21,High activity,High purity,Low endotoxin,Cell culture,Immune cell,Mammalian expression
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