- ￥2600 - 8800
- 上海经科
- 中国
- JK7532
- 2026年05月21日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
3 months at -20°C
- 英文名：
M-CSF R/CSF1R/CD115, His, Cynomolgus
- 库存：
现货
- 供应商：
上海经科化学科技有限公司
- 规格：
100μg/500μg
| 规格： | 100μg | 产品价格： | ￥2600.0 |
|---|---|---|---|
| 规格： | 500μg | 产品价格： | ￥8800.0 |
| Species | Cynomolgus | ||||
| Protein Construction |
|
||||
| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 56.3 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. |
| Synonyms | CD115; CSF1R; CSF-1-R; CSFR; FMSFIM2; M-CSF R; MCSFR; M-CSFR; C-FMS; FIM2; FMS; HDLS |
产品特点：
1. 【食蟹猴源天然序列】采用食蟹猴 M-CSFR（CSF1R/CD115）天然氨基酸序列，无突变，与食蟹猴体内天然蛋白结构完全一致，适配食蟹猴来源细胞的实验需求，无种属差异2. 【高活性高特异性】可高效结合 M-CSF 配体，ED₅₀ < 100 ng/mL（配体结合实验），可被 M-CSFR 特异性抗体识别，适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%，内毒素 < 0.5 EU/μg（LAL 法），无支原体、细菌、真菌等微生物污染，适配多种科研实验需求4. 【His 标签易纯化检测】哺乳动物细胞表达，C 端带 His 标签，可通过 Ni-NTA 亲和层析快速纯化，也可通过 His 标签抗体进行特异性检测5. 【稳定易保存】蛋白储存液配方优化，未开封 - 80℃可稳定保存 12 个月，-20℃可存 6 个月，避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 M-CSFR 蛋白结构与功能研究、巨噬细胞分化与免疫调控机制研究、非人灵长类疾病模型研究、细胞培养添加剂、药物筛选、抗体研发等
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