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- ￥5800 - 19200
- 上海经科
- 中国
- JK7512
- 2026年09月28日
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![重组蛋白 HLA-A & B2M & KRAS G12D (VVVGADGVGK) Monomer [Biotin] Human His Avi Biotin](https://img1.dxycdn.com/p/s14/2026/0615/891/6378262171915236602.png!wh200)
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- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
3 months at -20°C
- 英文名：
TREM2[Biotin], His & Avi, Human
- 库存：
现货
- 供应商：
上海经科化学科技有限公司
- 规格：
100μg/500μg
| 规格： | 100μg | 产品价格： | ￥5800.0 |
|---|---|---|---|
| 规格： | 500μg | 产品价格： | ￥19200.0 |
| Species | Human | ||||||
| Protein Construction |
|
||||||
| Conjugate | Biotin | ||||||
| Purity | > 95% as determined by Bis-Tris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 20.3 kDa | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 30-45 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia. |
| Synonyms | PLOSL2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c |
产品特点：
1. 【人源天然序列】采用人源 TREM2 天然氨基酸序列，无突变，与体内天然蛋白结构完全一致，可特异性结合 TREM2 配体2. 【高活性高特异性】可特异性结合 TREM2 抗体，ED₅₀ < 100 ng/mL（抗体结合实验），可被 TREM2 特异性抗体识别，适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%，内毒素 < 0.2 EU/μg（LAL 法），适配免疫细胞培养、体内免疫实验等敏感场景需求4. 【多标签易纯化检测】哺乳动物细胞表达，N 端带 Avi 标签、C 端带 His 标签，可通过 Ni-NTA 亲和层析快速纯化，也可通过 Avi/His 标签抗体、生物素亲和素系统进行特异性检测5. 【稳定易保存】蛋白储存液配方优化，未开封 - 80℃可稳定保存 12 个月，-20℃可存 6 个月，避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 TREM2 蛋白结构与功能研究、免疫调控机制研究、神经退行性疾病机制研究、细胞培养添加剂、药物筛选、抗体研发等
TREM2, 髓系细胞触发受体 2, 人源，人，重组蛋白，重组，高活性，高纯度，低内毒素，生物素标记，His 标签，Avi 标签，细胞培养，免疫细胞，科研实验，哺乳动物细胞表达，Human,TREM2,Recombinant protein,Biotin conjugated,His-tagged,Avi-tagged,High activity,High purity,Low endotoxin,Cell culture,Immune cell,Mammalian expression
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