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- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
3 months at -20°C
- 英文名:
ROR1, His & Avi, Human/Cynomolgus/Rhesus macaque
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 规格:
100μg/500μg
| 规格: | 100μg | 产品价格: | ¥3200.0 |
|---|---|---|---|
| 规格: | 500μg | 产品价格: | ¥10500.0 |
| Species | Human/Cynomolgus/Rhesus macaque | ||||||
| Protein Construction |
|
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| Purity | > 95% as determined by Bis-Tris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 44.9 kDa | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4 . | ||||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members. |
| Synonyms | ROR1; NTRKR1; dJ537F10.1 |
产品特点:
1. 【多物种同源序列】采用人 / 食蟹猴 / 恒河猴同源 ROR1 天然氨基酸序列,无突变,与天然蛋白结构完全一致,可特异性结合 ROR1 抗体及配体2. 【高活性高特异性】可特异性结合 ROR1 抗体,ED₅₀ < 100 ng/mL(抗体结合实验),可被 ROR1 特异性抗体识别,适用于抗体筛选、肿瘤机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.2 EU/μg(LAL 法),适配细胞培养、体内肿瘤实验等敏感场景需求4. 【双标签易纯化检测】C 端带 His 标签、N 端带 Avi 标签,可通过 Ni-NTA 亲和层析快速纯化,也可通过标签抗体进行特异性检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 ROR1 蛋白结构与功能研究、肿瘤侵袭转移机制研究、抗体制备与筛选、药物靶点验证、细胞培养添加剂等
ROR1, 人源,食蟹猴源,恒河猴源,重组蛋白,重组,高活性,高纯度,低内毒素,His 标签,Avi 标签,肿瘤研究,细胞培养,科研实验,哺乳动物细胞表达 Human,Cynomolgus,Rhesus macaque,ROR1,Recombinant protein,His-tagged,Avi-tagged,High activity,High purity,Low endotoxin,Tumor research,Cell culture,Mammalian expression
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文献和实验ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.
resource for health care providers. J. Med. Libr. Assoc. 94:343‐348. Rhesus Macaque Genome Sequencing and Analysis Consortium, Gibbs, R.A., Rogers, J., Katze, M.G., Bumgarner, R
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