- ￥3500 - 11500
- 上海经科
- 中国
- JK8820
- 2026年05月21日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
3 months at -20°C
- 英文名：
TNFR1/CD120a/TNFRSF1A, His, Cynomolgus
- 库存：
现货
- 供应商：
上海经科化学科技有限公司
- 规格：
100μg/500μg
| 规格： | 100μg | 产品价格： | ￥3500.0 |
|---|---|---|---|
| 规格： | 500μg | 产品价格： | ￥11500.0 |
| Species | Cynomolgus | ||||
| Protein Construction |
|
||||
| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 21.62 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling. |
| Synonyms | TNF-R1; TNF-RI; FPF; TBP1; TNF-R55; TNFAR; TNFR60; p55; p60; MS5; p55-R; TNFR1-d2 |
产品特点：
1. 【食蟹猴源天然序列】采用食蟹猴源 TNFR1/CD120a/TNFRSF1A 天然氨基酸序列，无突变，与天然蛋白结构完全一致，可特异性结合 TNF 配体2. 【高活性高特异性】可特异性结合 TNFR1 抗体，ED₅₀ < 100 ng/mL（抗体结合实验），可被 TNFR1 特异性抗体识别，适用于抗体筛选、炎症免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%，内毒素 < 0.2 EU/μg（LAL 法），适配细胞培养、体内动物实验等敏感场景需求4. 【His 标签易纯化检测】C 端带 His 标签，可通过 Ni-NTA 亲和层析快速纯化，也可通过 His 标签抗体进行特异性检测5. 【稳定易保存】蛋白储存液配方优化，未开封 - 80℃可稳定保存 12 个月，-20℃可存 6 个月，避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 TNFR1 蛋白结构与功能研究、炎症与免疫调控机制研究、抗体制备与筛选、药物靶点验证、细胞培养添加剂等
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