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- 文献和实验
- 技术资料
- 供应商:
武汉研升生物科有限公司
- 检测范围:
0.16-10 ng/mL
- 检测方法:
Sandwich
- 适应物种:
Mouse
- 样本:
serum, plasma and other biological fluids
- 灵敏度:
0.049 ng/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1820.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2600.0 |
| 中文名称 | 小鼠线粒体丝氨酸/苏氨酸蛋白激酶PINK1(PINK1)酶联免疫吸附检测试剂盒 |
| 英文名称 | Mouse PINK1(Serine/threonine-protein kinase PINK1, mitochondrial) ELISA Kit |
| 别名 | PTEN-induced putative kinase protein 1; BRPK |
| 货号 | ELK9917 |
| 反应种属 | Mouse |
| 检测类型 | Sandwich |
| 灵敏度 | 0.049 ng/mL |
| 标准品 | 10 ng/mL |
| 检测范围 | 0.16-10 ng/mL |
| 样本类型 | serum, plasma and other biological fluids |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PINK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PINK1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PINK1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PINK1 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Tumor immunity; |

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文献和实验Assays for Cyclin-Dependent Kinase Inhibitors
Cyclin-dependent kinases (CDK) are serine/threonine kinases that regulate cell cycle control and progression (1 ,2 ). A CDK holoenzyme complex is active if associated with its cyclin partner and if the complex is phosphorylated at specific
化损伤和结石形成的机制。该纳米药物平台展现出优异的抗氧化能力、胃肠道稳定性及肾近曲小管靶向富集特性,在小鼠模型中显著减少草酸钙晶体沉积并缓解肾小管损伤且无系统性毒性。研究创新性地揭示了TOMM22作为PINK1-Parkin线粒体自噬关键开关的角色,为肾结石等线粒体功能障碍疾病提供了精准治疗靶点和新型口服纳米药物策略。 03 靶点:STK40 应用:肝癌免疫治疗 来源:Targeting tumor-intrinsic STK40 induces immune vulnerability
位升高),不知道我的这个结果是否可以说明gsk活性降低了?还是一定需要第九位的结果才能解释这个问题?似乎也有些人说216特异性不强,没有第九位有说服力,不是很能理解这其中的原因,再次感谢你! ylhuang0502 As for the GSK phosphorylation, it is clear now that, GSK serine phosphorylation (S9 for beta and S21 for alpha
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