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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉研升生物科有限公司
- 检测范围:
15.63-1000 pg/mL
- 检测方法:
Sandwich
- 适应物种:
Rat
- 样本:
Tissue homogenates, cell lysates and other biological fluids.
- 灵敏度:
5.9 pg/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1960.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2800.0 |
| 中文名称 | 大鼠AMPA离子能谷氨酸受体1(GRIA1)酶联免疫吸附检测试剂盒 |
| 英文名称 | Rat GRIA1(Glutamate Receptor, Ionotropic, AMPA 1) ELISA Kit |
| 别名 | GLUH1; GLUR1; GLURA; HBGR1; GluR-K1; AMPA-selective glutamate receptor 1 |
| 货号 | ELK6368 |
| 反应种属 | Rat |
| P19490 | P19490 |
| 检测类型 | Sandwich |
| 灵敏度 | 5.9 pg/mL |
| 标准品 | 1000 pg/mL |
| 检测范围 | 15.63-1000 pg/mL |
| 样本类型 | Tissue homogenates, cell lysates and other biological fluids. |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GRIA1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GRIA1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat GRIA1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat GRIA1 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Neuro science; |

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文献和实验Methods for Evaluation of Positive Allosteric Modulators of Glutamate AMPA Receptors
modulation of the α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA) subtype of glutamate receptors has been proposed as a novel therapeutic approach, because these receptors mediate the majority of rapid excitatory neurotransmission
Functional Study of Glutamate Receptor Channels in Brain Slices
Glutamate is the major excitatory neurotransmitter in the central nervous system (CNS). Glutamate binds to and activates receptors coupled to both ligand-gated ion channels (ionotropic) and G proteins (metabotropic
Solubilization and Purification of a Functional Ionotropic Excitatory Amino Acid Receptor
Excitatory amino acid receptors are the predominant type of neurotransmitter receptor in the vertebrate central nervous system (CNS). They are membrane-spanning proteins that mediate the stimulatory actions of glutamate and possibly other related
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