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- 文献和实验
- 技术资料
- 供应商:
武汉益普生物科有限公司
- 检测范围:
0.16-10 ng/mL
- 检测方法:
Sandwich
- 适应物种:
Human
- 样本:
tissue homogenates, cell lysates and other biological fluids
- 灵敏度:
0.056 ng/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1820.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2600.0 |
| 中文名称 | 人杀伤细胞免疫球蛋白样受体3DL1(KIR3DL1)酶联免疫吸附检测试剂盒 |
| 英文名称 | Human KIR3DL1(Killer Cell Immunoglobulin Like Receptor 3DL1) ELISA Kit |
| 别名 | CD158E; HLA-BW4-specific inhibitory NK cell receptor; CD158 antigen-like family member E; Natural killer-associated transcript 3; p70 NK receptor CL-2/CL-11 |
| 货号 | ELK3894 |
| 反应种属 | Human |
| P43629 | P43629 |
| 检测类型 | Sandwich |
| 灵敏度 | 0.056 ng/mL |
| 标准品 | 10 ng/mL |
| 检测范围 | 0.16-10 ng/mL |
| 样本类型 | tissue homogenates, cell lysates and other biological fluids |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KIR3DL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KIR3DL1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human KIR3DL1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human KIR3DL1 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Signal transduction;Tumor immunity;Infection immunity;Immune molecule;Immunodeficiency;Autoimmunity; |

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文献和实验Overview of the Killer Cell Immunoglobulin-Like Receptor System
and the maintenance of pregnancy. Human NK cells largely use a family of germ-line encoded killer cell immunoglobulin-like receptors (KIR) to respond to the perturbations from self-HLA class I molecules present on infected, malignant, or HLA-disparate fetal
. The killer-cell immunoglobulin-like receptor (KIR) family is a set of receptors that are very polymorphic with regard to gene content, expression level, and expression pattern. KIRs are responsible for the induction of a NK cell alloreactive response
Killer Cell Immunoglobulin-Like Receptors (KIR) Typing by DNA Sequencing
DNA sequencing is a powerful technique for identifying allelic variation within the natural killer cell immunoglobulin-like receptor genes. Because of the relatively large size of the KIR genes, each locus is amplified
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