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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉益普生物科有限公司
- 检测范围:
31.25-2000 pg/mL
- 检测方法:
Sandwich
- 适应物种:
Human
- 样本:
serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
- 灵敏度:
11.2 pg/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1680.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2400.0 |
| 中文名称 | 人二级淋巴组织趋化因子(SLC)酶联免疫吸附检测试剂盒 |
| 英文名称 | Human SLC(Secondary Lymphoid Tissue Chemokine) ELISA Kit |
| 别名 | CCL21; 6Ckine; CKb9; ECL; SCYA21; TCA4; ECL; Chemokine(C-C-Motif)Ligand 21; Beta Chemokine Exodus-2; Efficient Chemoattractant For Lymphocytes |
| 货号 | ELK1409 |
| 反应种属 | Human |
| O00585 | O00585 |
| 检测类型 | Sandwich |
| 灵敏度 | 11.2 pg/mL |
| 标准品 | 2000 pg/mL |
| 检测范围 | 31.25-2000 pg/mL |
| 样本类型 | serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SLC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SLC. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human SLC, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human SLC in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Cytokine;Tumor immunity;Infection immunity; |

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文献和实验A chemokine-driven positive feedback loop organizes lymphoid follicles
Lymphoid follicles are B-cell-rich compartments of lymphoid organs that function as sites of B-cell antigen encounter and differentiation. CXC chemokine receptor-5 (CXCR5) is required for B-cell migration to splenic
Chemokine Overexpression in the Skin by Biolistic DNA Delivery
Chemokines are a family of small, secreted proteins that function in leukocyte and tumor cell trafficking and recruiting. CC chemokine ligand 21 (CCL21)/secondary lymphoid chemokine (SLC) belongs to the inflammatory subgroup of chemokines
趋化因子根据体内表达状况分类 1.组成性表达的趋化因子 组成性表达的趋化因子通过配体―受体配对,通常在白细胞迁移和胚胎发育中起作用。这些趋化因子及其受体发现得较晚,主要是因为它们在体内的表达水平较低,但是它们对于功能性免疫系统的建立又极为重要。例如其中的基质衍生因子(SDF)与其受体CXCR4的单一或共同缺陷,都将导致胚胎致死。二级淋巴组织趋化因子(SLC)(CCL21)及其受体CCR7的敲除引起二级淋巴组织的严重缺陷。而B细胞趋化因子1(BCA
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