PDZ-RhoGEF Rabbit Polyclonal Antibody产品图

PDZ-RhoGEF Rabbit Polyclonal A

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  • ¥1200 - 2150
  • EnkiLife
  • APRab15944
  • 2026年04月17日
  • WB,IHC
  • Rabbit
  • Human,Mouse,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 形态:

      Liquid

    • 保存条件:

      Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    • 标记物:

      Unconjugated

    • 适应物种:

      Human,Mouse,Rat

    • 供应商:

      武汉恩玑生命科技有限公司

    • 宿主:

      Rabbit

    • 应用范围:

      WB,IHC

    • 规格:

      50uL/100uL

    规格:50uL产品价格:¥1200.0
    规格:100uL产品价格:¥2150.0

    产品概述

    产品名称(Product Name)

    PDZ-RhoGEF Rabbit Polyclonal Antibody

    描述(Description)

    Rabbit polyclonal Antibody

    宿主(Host)

    Rabbit

    应用(Application)

    WB,IHC

    种属反应性(Reactivity)

    Human,Mouse,Rat

     

    产品性能

    偶联物(Conjugation)

    Unconjugated

    修饰(Modification)

    Unmodified

    同种型(Isotype)

    IgG

    克隆(Clonality)

    Polyclonal

    形式(Form)

    Liquid

    存放说明(Storage)

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    储存溶液(Buffer)

    Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

    纯化方式(Purification)

    Affinity purification

     

    免疫原

    基因名(Gene Name)

    ARHGEF11

    别名(Alternative Names)

    ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF

    基因ID(Gene ID)

    9826

    蛋白ID(SwissProt ID)

    O15085

     

    产品应用

    稀释比(Dilution Ratio)

    WB 1:500-1:2000,IHC 1:50-1:300

    蛋白分子量(Molecular Weight)

     

    研究背景

    Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],domain:The poly-Pro region is essential for plasma membrane localization upon stimulation.,function:May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 RGSL (RGS-like) domain.,subcellular location:Translocated to the membrane upon stimulation.,subunit:Interacts with GNA12 and GNA13 through the RGS domain. Interacts with RHOA, PLXNB1 and PLXNB2. Interacts with SLC1A6.,tissue specificity:Ubiquitously expressed.,

     

    研究领域

    Regulation of Actin Dynamics; AMPK

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      Zealand White Rabbits and have them delivered to the ARC. Don’t put all your eggs in one basket only using one rabbit. Let them get accustomed to there home there for two weeks before the first pre-bleed. Pre-bleed        

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Generation and Selection of Rabbit Antibody Libraries by Phage Display

      The rabbit antibody repertoire is an exceptional source for both polyclonal antibodies (pAbs) and monoclonal antibodies (mAbs) that combine high specificity with high avidity and affinity, respectively. In contrast to rabbit pAbs

    图标技术资料

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