Synaptotagmin 1/2 (phospho Thr202/199) Rabbit Polyclonal Antibody产品图

Synaptotagmin 1/2 (phospho Thr

202/199) Rabbit Polyclonal Antibody
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  • ¥1350 - 2250
  • EnkiLife
  • APRab05506
  • 2026年04月17日
  • WB,IHC,ICC/IF,ELISA
  • Rabbit
  • Human,Mouse,Rat
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 形态:

      Liquid

    • 保存条件:

      Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    • 标记物:

      Unconjugated

    • 适应物种:

      Human,Mouse,Rat

    • 供应商:

      武汉恩玑生命科技有限公司

    • 宿主:

      Rabbit

    • 应用范围:

      WB,IHC,ICC/IF,ELISA

    • 规格:

      50uL/100uL

    规格:50uL产品价格:¥1350.0
    规格:100uL产品价格:¥2250.0

    产品概述

    产品名称(Product Name)

    Synaptotagmin 1/2 (phospho Thr202/199) Rabbit Polyclonal Antibody

    描述(Description)

    Rabbit polyclonal Antibody

    宿主(Host)

    Rabbit

    应用(Application)

    WB,IHC,ICC/IF,ELISA

    种属反应性(Reactivity)

    Human,Mouse,Rat

     

    产品性能

    偶联物(Conjugation)

    Unconjugated

    修饰(Modification)

    Phosphorylated

    同种型(Isotype)

    IgG

    克隆(Clonality)

    Polyclonal

    形式(Form)

    Liquid

    存放说明(Storage)

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    储存溶液(Buffer)

    Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

    纯化方式(Purification)

    Affinity purification

     

    免疫原

    基因名(Gene Name)

    SYT1/SYT2

    别名(Alternative Names)

    SYT1; SVP65; SYT; Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT2; Synaptotagmin-2; Synaptotagmin II; SytII

    基因ID(Gene ID)

    6857/127833

    蛋白ID(SwissProt ID)

    P21579/Q8N9I0

     

    产品应用

    稀释比(Dilution Ratio)

    WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000

    蛋白分子量(Molecular Weight)

    60kDa

     

    研究背景

    The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010],cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain mediates interaction with SV2A and STN2.,function:May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subcellular location:Synaptic vesicles and chromaffin granules.,subunit:Homotetramer (Probable). Interacts with SCAMP5, STN2, SV2A, SV2B, SV2C and RIMS1. Forms a complex with SV2B, syntaxin 1 and SNAP25.,

     

    研究领域

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    图标文献和实验
    相关实验
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    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

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