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文献和实验Screening of Novel Inhibitors of HIV-1 Reverse Transcriptase with a Reporter Ribozyme Assay
“Highly active anti-retroviral therapy (HAART)” is currently the standard treatment for human immunodeficiency virus (HIV). This treatment consists of a cocktail of two reverse transcriptase (RT) inhibitors and a protease inhibitor
Screening Inhibitors of P. berghei Blood Stages Using Bioluminescent Reporter Parasites
We describe two improved assays for in vitro and in vivo screening of inhibitors and chemicals for antimalarial activity against blood stages of the rodent malaria parasite, Plasmodium berghei . These assays are based on the determination
Multiplexed Flow Cytometry: High-Throughput Screening of Single-Chain Antibodies
and quantity of data, combined with significant reductions in analysis time and antigen consumption, provide notable advantages over other standard screening methods, such as ELISA. By combining HT screening capabilities with multiplex technology
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