3′-deoxy Thymidine-33939-100 m

Use of a Novel 5′‐Regioselective Phosphitylating Reagent for One‐Pot Synthesis of Nucleoside 5′‐Triphosphates from Unprotected Nucleosides

thymidine 5′‐triphosphate (TTP, 8t O ). The crude sample can be analyzed on a Welchrom C18 (or Ultisil C18) reversed‐phase column (4.6 × 250 mm) measured at 260 nm at a flow of 1.0 mL/min using a linear gradient of 0% to 40% buffer B in 20 min. Buffer A: 20

Modification of the 5′ Terminus of Oligodeoxyribonucleotides for Conjugation with Ligands

to a controlled‐pore glass (CPG) support Nitrogen gas 40 mg/mL anhydrous 1,1′‐carbonyldiimidazole in anhydrous dioxane

霍奇金病（Hodgkin′s disease）

　　霍奇金病（H0dgkin′s disease）又名淋巴网状细胞肉瘤是一种慢性进行性、无痛的淋巴组织肿瘤，其原发瘤多呈离心性分布，起源于一个或一组淋巴结，以原发于颈淋巴结者较多见，逐渐蔓延至邻近的淋巴结，然后侵犯脾、肝、骨髓和肺等组织。由于发病的部位不同，其临床表现多种多样。 　　5岁以前很少发病，5岁以后逐渐增多，青春期发病率明显增多，15～34岁为高峰。发病者男性多于女性。男女比例在5～11岁为3∶1，11～19岁为1．5∶1。 　　【临床