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文献和实验Chimerization of a Monoclonal Antibody for Treating Hodgkin's Lymphoma
Conventionally, monoclonal antibodies (MAbs) are generated by fusing B cells from an immunized animal with myeloma cells from the same species (1 ). Several murine MAb have already been employed for in vivo diagnosis and therapy, including
Purification of Recombinant Poly(ADP-Ribose) Polymerases
affinity column are removed on the high-performance strong cations exchanger Source™ 15S matrix. The columns connected to an �KTA™ purifier system allow the purification of PARPs in 3 days with a high-yield recovery. As described in the protocol
Mouse Strains and Genetic Nomenclature
. We also provide some guidance to make the best possible choice when establishing an experimental protocol. Curr. Protoc. Mouse Biol. 1:213?238. © 2011 by John Wiley & Sons, Inc. Keywords: inbred strains; congenic strains; recombinant inbred
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