- ￥2588 - 7788
- abinScience
- France
- YP926026
- 2026年04月13日
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Mouse
- General
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a (Need Ca2+)
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
单克隆
- 适应物种：
General
- 保质期：
12 months
- 级别：
一抗
- 供应商：
武汉研升生物科技有限公司
- 宿主：
Mouse
- 应用范围：
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- 抗体英文名：
Research Grade Sphingomab
- 规格：
100μg/1mg
| 规格： | 100μg | 产品价格： | ￥2588.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥7788.0 |
| 产品名 | Research Grade Sphingomab |
| 货号 | YP926026 |
| 别名 | LT1002 |
| 表达系统 | Mammalian Cells |
| 靶标 | S1P, Sphingosine-1-phosphate |
| Accession号 | CAS: 1031360-18-5 |
| 宿主 | Mouse |
| 种属反应性 | General |
| 克隆性 | Monoclonal |
| 同种型 | IgG2a (Need Ca2+) |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Adenosine 3', 5'-cyclic monophosphate (cAMP) is a key second messenger molecule in intracellular signal transduction. Monitoring cAMP levels is one of the most common ways to screen for agonists and antagonists of G protein–coupled receptors(GPCRs). Bioyeargene cAMP ELISA Kit is based on the competition between HRP-labeled cAMP and free cAMP for fixed amounts of mouse monoclonal anti-cAMP antibody(cAMP MAb) binding sites. Because the concentration of the HRP-labeled cAMP is held constant while the concentration of cAMP varies, the amount of HRP-labeled cAMP that is able to bind to the cAMP MAb will be inversely proportional to the concentration of cAMP in the well. This antigen-antibody complex binds to the goat anti-mouse IgG that has been previously attached to the well. The plate is washed to remove any unbound reagents and then developed. The ELISA typically displays an IC50(50% B/B0) of approximately 12 pmol/mL and a detection limit of approximately 0.15 pmol/mL. • Sphingosine 1-phosphate: Lipid signaling in pathology and therapy., PMID:31624181 • Sphingosine-1-phosphate (S1P) in ovarian physiology and disease., PMID:31455516 • Sphingosine-1-phosphate (S1P) receptors: Promising drug targets for treating bone-related diseases., PMID:32155312 • Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells., PMID:37634735 • Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology., PMID:32278039 • Sphingosine 1-Phosphate (S1P)/ S1P Receptor Signaling and Mechanotransduction: Implications for Intrinsic Tissue Repair/Regeneration., PMID:31703256 • Sphingosine 1-phosphate (S1P) receptor modulators as an induction and maintenance therapy for ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials., PMID:38153524 • S1P (Sphingosine-1-Phosphate)-Induced Vasodilation in Human Resistance Arterioles During Health and Disease., PMID:36070401 • Sphingosine 1-phosphate (S1P) signalling: Role in bone biology and potential therapeutic target for bone repair., PMID:28855094 • Sphingosine 1-phosphate signalling., PMID:24346695 |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |
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文献和实验Characterization and Quality Control of Antibodies Used in ChIP Assays
epigenetics research tools based on everyday’s researcher’s needs by providing batch-specific fully characterized ChIP-grade antibodies.
相关专题 his method was successful in our lab using prostate tissue and for our specific objectives. Investigators must be aware that they will need to tailor the following protocol for their own research objectives
®尤其在皮肤组织的表皮分离和上皮层细胞培养中获得了广泛的应用。Dispase®I与Dispase®II两者的差别在于纯度的不同，Dispase®I经过滤除菌，且每mg Dispase®I的纯度和酶活远高于Dispase®II。 罗氏高纯度研究级别酶混合物Liberase Research Grade Enzyme Blends Liberase Research Grade Enzyme Blends包含了一系列酶混合物，它们由不同比例的中性蛋白酶（非梭菌蛋白酶）和高纯
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