- ￥598 - 2488
- abinScience
- France
- HB714026
- 2026年04月13日
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Humanized
- Human
企业认证
相关产品推荐更多 >
PFKFB2 Polyclonal Antibody（多克隆抗体）, HRP conjugated | PFKFB2 Antibody, HRP conjugated | PFKFB2抗体, HRP conjugated
￥880
HGS Polyclonal Antibody（多克隆抗体） | HGS Antibody | HGS抗体
￥880
H2AFB1 Polyclonal Antibody（多克隆抗体）, Biotin conjugated | H2AFB1 Antibody, Biotin conjugated | H2AFB1抗体, Biotin conjugated
￥880
Anti-HRSV-A F/Fusion glycoprotein F0 Antibody (HNK20-hu10)
￥1338
ASB13 Polyclonal Antibody（多克隆抗体）, HRP conjugated | ASB13 Antibody, HRP conjugated | ASB13抗体, HRP conjugated
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1-kappa
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
12 months
- 级别：
一抗
- 供应商：
武汉研升生物科技有限公司
- 宿主：
Humanized
- 应用范围：
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- 抗体英文名：
Research Grade Pivekimab
- 规格：
100μg/1mg
| 规格： | 100μg | 产品价格： | ￥598.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥2488.0 |
| 产品名 | Research Grade Pivekimab |
| 货号 | HB714026 |
| 别名 | G4723A2234335-84-1 |
| 表达系统 | Mammalian Cells |
| 靶标 | IL-3R subunit alpha, IL-3 receptor subunit alpha, CD123, Interleukin-3 receptor subunit alpha, IL3R, IL-3R-alpha, IL3RA, IL-3RA |
| Accession号 | P26951 |
| 宿主 | Humanized |
| 种属反应性 | Human |
| 克隆性 | Monoclonal |
| 同种型 | IgG1-kappa |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Talacotuzumab (TAL, JNJ-56022473) is an IgG1 monoclonal antibody targeting CD123 preferentially via antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells and has been shown to induce potent in vitro ADCC against IL3RA-expressing AML blasts/LSC and to reduce leukemic cell growth in murine xenograft models of human AML. In addition, the antibody inhibits signaling by IL-3, the main ligand of CD123, to reduce the proliferation of leukemic progenitor cells. • CD123 and its potential clinical application in leukemias., PMID:25445480 • Interleukin-3 receptor in acute leukemia., PMID:14671644 • IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway., PMID:29238040 • The role of interleukin-3 in classical Hodgkin's disease., PMID:15621820 • IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice., PMID:27183574 • New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells., PMID:17667524 • Receptor cross-linking on human plasmacytoid dendritic cells leads to the regulation of IFN-alpha production., PMID:17056507 • AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells., PMID:25879549 • Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice., PMID:16882709 • SL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemia., PMID:24942980 |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Characterization and Quality Control of Antibodies Used in ChIP Assays
epigenetics research tools based on everyday’s researcher’s needs by providing batch-specific fully characterized ChIP-grade antibodies.
相关专题 his method was successful in our lab using prostate tissue and for our specific objectives. Investigators must be aware that they will need to tailor the following protocol for their own research objectives
®尤其在皮肤组织的表皮分离和上皮层细胞培养中获得了广泛的应用。Dispase®I与Dispase®II两者的差别在于纯度的不同，Dispase®I经过滤除菌，且每mg Dispase®I的纯度和酶活远高于Dispase®II。 罗氏高纯度研究级别酶混合物Liberase Research Grade Enzyme Blends Liberase Research Grade Enzyme Blends包含了一系列酶混合物，它们由不同比例的中性蛋白酶（非梭菌蛋白酶）和高纯
技术资料暂无技术资料 索取技术资料
