- ￥598 - 2488
- abinScience
- France
- HF813026
- 2026年04月13日
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Humanized
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1-nd
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
12 months
- 级别：
一抗
- 供应商：
武汉研升生物科技有限公司
- 宿主：
Humanized
- 应用范围：
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- 抗体英文名：
Research Grade Fontolizumab
- 规格：
100μg/1mg
| 规格： | 100μg | 产品价格： | ￥598.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥2488.0 |
| 产品名 | Research Grade Fontolizumab |
| 货号 | HF813026 |
| 别名 | HuZAF, 326859-36-3 |
| 表达系统 | Mammalian Cells |
| 靶标 | Interferon gamma, IFN-gamma, Immune interferon, IFNG |
| Accession号 | P01579 |
| 宿主 | Humanized |
| 种属反应性 | Human |
| 克隆性 | Monoclonal |
| 同种型 | IgG1-nd |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH). • Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation., PMID:33606996 • Dysregulation in IFN-γ signaling and response: the barricade to tumor immunotherapy., PMID:37275859 • IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption., PMID:31566580 • IFN-γ Contributes to the Immune Mechanisms of Hypertension., PMID:36591357 • Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop., PMID:33766856 • Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche., PMID:29950724 • IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies., PMID:34906138 • Interferon-gamma release assay performance in northeastern Brazil: influence of the IFNG+874 A>T polymorphism., PMID:29787713 • Restraint of IFN-γ expression through a distal silencer CNS-28 for tissue homeostasis., PMID:37040761 • MUC1-C integrates activation of the IFN-γ pathway with suppression of the tumor immune microenvironment in triple-negative breast cancer., PMID:33495298 |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |
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文献和实验Characterization and Quality Control of Antibodies Used in ChIP Assays
epigenetics research tools based on everyday’s researcher’s needs by providing batch-specific fully characterized ChIP-grade antibodies.
相关专题 his method was successful in our lab using prostate tissue and for our specific objectives. Investigators must be aware that they will need to tailor the following protocol for their own research objectives
®尤其在皮肤组织的表皮分离和上皮层细胞培养中获得了广泛的应用。Dispase®I与Dispase®II两者的差别在于纯度的不同，Dispase®I经过滤除菌，且每mg Dispase®I的纯度和酶活远高于Dispase®II。 罗氏高纯度研究级别酶混合物Liberase Research Grade Enzyme Blends Liberase Research Grade Enzyme Blends包含了一系列酶混合物，它们由不同比例的中性蛋白酶（非梭菌蛋白酶）和高纯
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