- ¥1520
- BioXCell
- BE0285
- 2025年08月24日
- in vitro PD-L1 blockade Functional assays Immunohistochemistry (frozen) Flow cytometry
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- 详细信息
- 技术资料
- 抗体名：
PD-L1抗体
- 免疫原：
Mouse IgG2b, κ
- 亚型：
29E.2A3
- 级别：
InVivoMab Antibodies
- 抗原来源：
人，大小鼠
- 应用范围：
in vitro PD-L1 blockade Functional assays Immunohistochemistry (frozen) Flow cytometry
- 是否单克隆：
单克隆
- 抗体英文名：
nVivoMAb anti-human PD-L1 (B7-H1)
- 适应物种：
人
- 抗原：
29E.2A3
- 规格：
1mg
PD-L1抗体
Bio X cel公司l通过大规模的组织培养生产抗体，亲和层析法纯化抗体，我们提供的抗体都是高纯度、低内毒素，无防腐剂和稳定剂，适用于临床前研究
| Isotype | Mouse IgG2b, κ |
| Recommended Isotype Control(s) | InVivoMAb mouse IgG2b isotype control, unknown specificity(BE0086) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Full length human PD-L1 |
| Reported Applications |
|
| Endotoxin |
|
| Purity |
|
| Formulation |
|
| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
BioXcell BE0285-50MG InVivoMab anti-human PD-L1 (B7-H1) ￥24000
BioXcell BE0285-100MG InVivoMab anti-human PD-L1 (B7-H1) ￥35200
BioXcell BE0285-1MG InVivoMab anti-human PD-L1 (B7-H1) ￥1520
BioXcell BE0285-5MG InVivoMab anti-human PD-L1 (B7-H1) ￥5600
BioXcell BE0285-25MG InVivoMab anti-human PD-L1 (B7-H1) ￥14400
About InVivoMAb anti-human PD-L1 (B7-H1)
The 29E.2A3 monoclonal antibody reacts with human PD-L1 (programmed death ligand 1) also known as B7-H1 or CD274. PD-L1 is a 40 kDa type I transmembrane protein that belongs to the B7 family of the Ig superfamily. PD-L1 is expressed on T lymphocytes, B lymphocytes, NK cells, dendritic cells, as well as IFNγ stimulated monocytes, epithelial cells and endothelial cells. PD-L1 binds to its receptor, PD-1, found on CD4 and CD8 thymocytes as well as activated T and B lymphocytes and myeloid cells. Engagement of PD-L1 with PD-1 leads to inhibition of TCR-mediated T cell proliferation and cytokine production. PD-L1 is thought to play an important role in tumor immune evasion. Induced PD-L1 expression is common in many tumors and results in increased resistance of tumor cells to CD8 T cell mediated lysis. The 29E.2A3 antibody has been shown to block the binding of PD-1-Ig to PD-L1.
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