Phospho-STAT1 (Tyr701) Polycl
onal Antibody（多克隆抗体） | Phospho-STAT1 (Tyr701) Antibody | Phospho-STAT1 (Tyr701)抗体- ￥2454
- CUSABIO
- 武汉
- CSB-PA926759
- 2026年03月28日
- ELISA, WB, IHC
- Rabbit
- Human, Mouse, Rat
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- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around phosphorylation site of tyrosine 701 (T-G-Y(p)-I-K) derived from Human STAT1.
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
-20°C or -80°C
- 克隆性：
多克隆
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 抗原来源：
12个月
- 目录编号：
Homo sapiens (Human)
- 供应商：
武汉研升生物科技有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, WB, IHC
- 靶点：
STAT1
- 抗体英文名：
Phospho-STAT1 (Tyr701) Antibody
- 抗体名：
Phospho-STAT1 (Tyr701) Antibody
- 规格：
100μl
|
Product Name |
Phospho-STAT1 (Tyr701) Antibody |
|
Code |
CSB-PA926759 |
|
Aliases |
Signal transducer and activator of transcription 1 91kD antibody; CANDF7 antibody; DKFZp686B04100 antibody; IMD31A antibody; IMD31B antibody; IMD31C antibody; ISGF 3 antibody; ISGF-3 antibody; OTTHUMP00000163552 antibody; OTTHUMP00000165046 antibody; OTTHUMP00000165047 antibody; OTTHUMP00000205845 antibody; Signal transducer and activator of transcription 1 91kDa antibody; Signal transducer and activator of transcription 1 antibody; Signal transducer and activator of transcription 1, 91kD antibody; Signal transducer and activator of transcription 1-alpha/beta antibody; STAT 1 antibody; Stat1 antibody; STAT1_HUMAN antibody; STAT91 antibody; Transcription factor ISGF 3 components p91 p84 antibody; Transcription factor ISGF-3 components p91/p84 antibody; Transcription factor ISGF3 components p91/p84 antibody; XStat1 antibody |
|
Product Type |
Polyclonal Antibody |
|
Immunogen Species |
Homo sapiens (Human) |
|
Size |
100μl |
|
Uniprot ID |
P42224 |
|
Immunogen |
Peptide sequence around phosphorylation site of tyrosine 701 (T-G-Y(p)-I-K) derived from Human STAT1. |
|
Host Species |
Rabbit |
|
Species Reactivity |
Human, Mouse, Rat |
|
Tested Applications |
ELISA, WB, IHC; WB:1:500-1:1000 |
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Conjugate |
Non-conjugated |
|
Buffer |
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
|
Form |
Liquid |
|
Stroage |
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
|
Purification Method |
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi |
|
Target Names |
STAT1 |
|
Research Areas |
Epigenetics and Nuclear Signaling;Cancer;Signal transduction |
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文献和实验颠覆认知！为了生存，癌细胞竟主动断裂 DNA，Science 研究揭开背后机制
有丝分裂细胞死亡，这使得细胞的放疗敏感性提高。事实上，缺乏 CAD 或 ICAD 表达的癌细胞就表现出更高的放射敏感性。 图片来源：Science 此外，研究人员注意到 G2 细胞周期检查点控制的缺失导致不稳定核的发生率增加。这种基因组的不稳定性被认为是激活炎症性 STAT1 信号的一个强有力的分子模式信号。因此，研究人员评估了在野生型和 CAD 缺陷细胞中，发现 IR 后 STAT1 位点 Tyr701 的激活磷酸化。这表明，在 IR 后，CAD 缺陷细胞中 p-Tyr701 STAT1 升高
有丝分裂细胞死亡，这使得细胞的放疗敏感性提高。事实上，缺乏 CAD 或 ICAD 表达的癌细胞就表现出更高的放射敏感性。 图片来源：Science 此外，研究人员注意到 G2 细胞周期检查点控制的缺失导致不稳定核的发生率增加。这种基因组的不稳定性被认为是激活炎症性 STAT1 信号的一个强有力的分子模式信号。因此，研究人员评估了在野生型和 CAD 缺陷细胞中，发现 IR 后 STAT1 位点 Tyr701 的激活磷酸化。这表明，在 IR 后，CAD 缺陷细胞中 p-Tyr701 STAT1
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
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