Human Netrin G1

Lentiviral Vector Gene Transfer into Human T Cells

, and subsequent integration of the lentivirus genome do not occur in these cells unless they are activated via the T-cell receptor (TCR) and/or by cytokines inducing resting T cells to enter in G1b phase of the cell cycle. In T-cell-based gene therapy trials

Abrogation of the RB-p16Tumor Suppressor Pathway in Human Lung Cancer

There is compelling evidence that human lung cancers are characterized by disruption of several important physiological pathways that govern proliferation, apoptosis, intracellular signaling, and cell-cell interactions. Uncontrolled cellular

Human Gm, Km, and Am Allotypes and Their Molecular Characterization: A Remarkable Demonstration of Polymorphism

Human immunoglobulin allotypes are antigenic determinants (or “markers”) determined serologically, classically by hemagglutination inhibition, on the human immunoglobulin (IG) heavy and light chains. The allotypes have been identified