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- 文献和实验
- 技术资料
- 保存条件:
Store at -80°C.
- 保质期:
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
- 英文名:
Purified protein of Human receptor tyrosine kinase-like orphan receptor 2 (ROR2), residues 34-403aa, with C-terminal DDK tag, expressed in sf9, 20ug
- 供应商:
OriGene
- 规格:
20 ug
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文献和实验The epidermal growth factor (EGF) receptor possesses intrinsic protein-tyrosine kinase activity, and both overexpressed wild-type and mutated forms have been associated with many types of cancers. Therefore, understanding the mechanisms
Transmembrane Signaling by Receptor Oligomerization
(5 ), and that this is necessary for a biological response (6 ). Yarden and Schlessinger subsequently showed that the purified EGF receptor tyrosme kinase undergoes dimerization upon binding to EGF (7 ), and that the dimeric form of the receptor displays elevated tyrosme kinase
Isolation of Novel Substrates Using a Tyrosine Kinase Overlay/In Situ Assay
Identifying substrates of receptor and non-receptor protein tyrosine kinases (PTK), and how phosphorylation of these substrates affects signaling and cytoskeletal pathways, has been a key step in understanding the role of PTK in differentiation
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