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文献和实验GABA (γ-aminobutyric acid) receptors are among the most ubiquitous in the brain, having been identified (neurophysiologitally) in all regions and at all levels (e.g., Iversen, 1978 ). All neuronal cells respond to the iontophoretic application
Characterization of GABA Receptors
in this unit are ligand?binding assays for GABAA , GABAB , and the homomeric ? GABAA (formerly GABAC ) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining
A Homogeneous Assay to Assess GABA Transporter Activity
a convenient functional uptake assay for GABA transport into cell lines transiently transfected with GABA transporter?1 (GAT?1) and other GAT isoforms. This facile, homogeneous assay allows for the determination of K m , V max , and K i values. The assay
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