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- 2026年02月22日
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文献和实验Detection of Brain Pathology by Magnetic Resonance Imaging of Iron Oxide Micro-particles
when images obtained by conventional MRI look normal. Indeed, our selectively targeted micro-particles of iron oxide have revealed the early presence of cerebral malaria pathology and ongoing MS-like plaques in clinically relevant models of disease.
Magnetic Resonance Imaging of Brain Inflammation Using Microparticles of Iron Oxide
from their high iron content and are significantly greater than that of ultra-small particles of iron oxide (USPIO), commonly used for MRI. Due to their size and incompressible nature, MPIO are less susceptible to nonspecific vascular egress or uptake
allowing the visualization of anatomical areas without in-depth limitations. These features make MRI particularly adapted for cellular imaging. The use of “ (ultrasmall) superparamagnetic iron oxide ” particles [(U) SPIO] offers the adequate sensitivity
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