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北京柏瑞图科技有限公司
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文献和实验【求助】请教一个很白痴很基础的问题:到底什么是soluble receptor?
of a cellular response to that ligand. Studies conducted in the early 1990s suggested that the type II interleukin-1 receptor (IL-1RII) binds IL-1 but is not part of a signaling receptor complex. Evidence suggests that IL-1RII, in transmembrane or soluble (sIL
Detection of Class Switching and IgE Synthesis in Human B Cells
We observed that mast cells, as other cells expressing the CD40 ligand CD154, can trigger IgE synthesis in B cells in the presence of interleukin (IL)-4. Numerous complementary techniques can be used to follow the succession of molecular
8 The Recovery of Immunoglobulin Sequences from Single Human B Cells by Clonal Expansion
chain reaction (PCR) amplification of their variable-region genes, thereby immortalizing the VH and VL regions from individual human B cells. The method relies on the clonal expansion of single B cells in which cell-cell interactions (CD40-CD40
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