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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Partially purified cell membrane antigens from fresh leukemia cells.
- 亚型:
IgG1
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX75137
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Mouse
- 应用范围:
WB, IHC-Fr, FACS, IP
- 浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
CD10
- 抗体英文名:
CD10 antibody [SN5c]
- 抗体名:
CD10 抗体 [SN5c]
- 规格:
100 μg
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文献和实验monoclonal antibody production fusion
centrifuge at 1200 rpm, 5 min, 37ѓC. aspirate the supernatant (SN) with a Pasteur pipette (all till the last drop!!!) gently break the pellet by tapping of the bottom of the tube. place the tube on 37ѓC water bath; add slowly, dop by drop
of patients with open heart surgery the expression of the membrane peptidases neprilysin/CD10 and aminopeptidase N/CD13, was determined on granulocytes in comparison to the monocytic HLA-DR expression. We used the QuantiBRITE™ flow cytometry
「神药」再显威!杨黄浩等让二甲双胍扮演 PD-L1 「单抗」角色,提高治疗效果
封闭肿瘤细胞表面的 PD-L1 而达到治疗效果。这种阻断作用是暂时的,可能由于细胞内 PD-L1 主动重新分布到细胞膜而减弱,导致治疗效果受损。 福州大学的杨黄浩团队将二甲双胍「老药新用」,研制出了一种自组装的纳米片(MS NPs)。该纳米片是由二甲双胍 Met(作为一种免疫佐剂)和抗癌药物 SN38(即 7 - 乙基 - 10 - 羟基喜树碱,作为一种 DNA 拓扑异构酶 I 抑制剂)组装而成。其作用机制不同于传统的抗体类 ICBs,这种纳米片主要是干扰内源性的 PD-L1 表达,进而达到了类似
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