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- 2026年02月13日
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文献和实验Antibody–drug conjugates (ADCs) combine the selectivity of a monoclonal antibody with the killing potency of a cytotoxic drug. For an antibody to function as a successful component of an ADC, it needs to bind to the target antigen
AntibodyDrug Conjugate Payloads
Toxin payloads, or drugs, are the crucial components of therapeutic antibody–drug conjugates (ADCs). This review will give an introduction on the requirements that make a toxic compound suitable to be used in an antitumoral ADC
Polysaccharicb-Conjugate Vaccines
)saccharides (2 , 3 ). We now know that the carrier proteins ensure the involvement of T-helper lymphocytes in the activation of the haptenor polysaccharide-specific antibody producing B lymphocytes (Fig. 1 ). In contrast to small molecules or haptens
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