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文献和实验Cell Death Differ:中大五院黄曦团队发现新冠病毒引起肺损伤的分子机制
病理发生。然而,SARS-CoV-2 感染引起肺细胞凋亡的机制仍不清楚。 2022 年 1 月 13 日,中山大学附属第五医院黄曦课题组在 Cell death & differentiation 上发表了题为 SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK 研究性论文。该研究证实了病毒膜(M)蛋白会通过靶向 BOK 分子,介导肺
Chain Shuffling to Modify Properties of Recombinant Immunoglobulins
, as well as the extensive knowledge of how they interact with their antigen (Ag) targets, have made them favorite targets for modification by this approach. The binding site of Abs can be described as a set of modules that together make up the Ag-binding site. These modules
Expression and Isolation of Recombinant Antibody Fragments in E. coli
Central to the rapid growth in the study and application of recombinant antibodies in recent years is the ability to reliably and cost-effectively produce large quantities of functional protein. In contrast to glycosylated whole monoclonal
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