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- 2026年01月22日
- WB
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
Caspase-9 Monoclonal Antibody
- 应用范围：
WB
- 宿主：
Mouse
- 库存：
99
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态：
液体
- 亚型：
IgG2a
- 规格：
100μL/25μL
| 规格： | 100μL | 产品价格： | ￥2100.0 |
|---|---|---|---|
| 规格： | 25μL | 产品价格： | ￥800.0 |
Caspase-9 Monoclonal Antibody
| Verified Samples |
Verified Samples in WB: Hep G2, HeLa, THP-1
|
| Dilution |
WB 1:250-1:500
|
| Clonality |
Monoclonal
|
| Isotype |
IgG2a
|
| Immunogen |
Recombinant Human Caspase-9 protein expressed by E.coli
|
| Abbre |
Caspase-9
|
| Synonyms |
Apoptosis related cysteine peptidase, Apoptotic protease-activating factor 3, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9 subunit p10, ICE LAP6, ICE like apoptotic protease 6, ICE-like apoptotic protease 6, protein phosphatase 1, regulatory subunit 56, RNCASP9, MCH, Apoptotic protease Mch, PPP1R, ICE-LAP, CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase-9, Caspase 9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3 (APAF-3), ICE-like apoptotic protease 6 (ICE-LAP6)
|
| Swissprot |
P55211
|
| Calculated MW |
46 kDa
|
| Observed MW |
35 kDa;47 kDa
|
| Cellular Localization |
Cytoplasm, Nucleus, Mitochondrion
|
| Tissue Specificity |
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
|
| Concentration |
1 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
|
| Purification Method |
Protein A/G Purification
|
| Research Areas |
Cell Biology, Cancer, Metabolism
|
| Clone No. |
3B6
|
| Conjugation |
Unconjugated
|
| Background |
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
|
Caspase-9 Monoclonal AntibodyElabscience®拥有先进的单抗，多抗和流式抗体开发技术平台，提供8500+高品质抗体， 适用于胞内和胞外蛋白的鉴定、定量和定位研究。抗体已在多种应用中得到验证，包含 流式细胞术（Flow Cytometry）、 免疫印迹（WB）、 免疫组化（IHC/ICC）、 免疫（共）沉淀（IP/Co-IP）、 免疫荧光（IF） 等实验。抗体产品涉及多种生命科学研究领域，包括肿瘤、免疫、心血管、细胞生物学、神经科学、表观遗传学等。Elabscience®始终致力于提高抗体的质量和种类，以保障并加快您的研究进程。
Caspase-9 Monoclonal AntibodyStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Caspase-9 Monoclonal Antibody产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma，在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应，对应于抗原之不同部分可制成各种不同的抗体复合体。然而，因为一个产生抗体的细胞，只能产生一种抗体，所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种，可形成边产生抗体边增殖的 hybridoma，将每个杂种细胞进行克隆（无性繁殖系）培养，则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成，这样得到的就是单克隆抗体。此抗体在测定
Monoclonal Antibody Production
Order 6 six week old Balb/C mice and let the ARC know they are coming.Have your antigen ready for when they arrive.Once they get there earmark the mice and perform a pre-bleed on them to be used as an ELISA control for monitoring the titer
Monoclonal Antibody-Based Immunoassays
An immunoassay may be defined as an assay that employs an immunological reagent, usually an antibody, to confer specificity for the ligand being measured. As a corollary to this, the discovery, and subsequent development, of monoclonal
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