BMP-9/GDF2细胞因子,重组人骨形态发生蛋白9,重组蛋

重组人骨形态发生蛋白9 (BMP-9/GDF2) 细胞因子

货号：PRP1221

英文全称：Human BMP-9/GDF2 protein, S tag

产品概述

本品为高纯度重组人GDF2蛋白，通过大肠杆菌表达系统制备，N端带有S标签，是一种重要的细胞因子，属于TGF-β超家族成员。该产品以冻干粉形式提供，具有低内毒素特性，适用于细胞培养及相关体外研究。

关键特性

• 高纯度：经SDS-PAGE验证，纯度 > 96%
• 低内毒素：LAL法检测，每微克蛋白内毒素含量 < 1 EU
• 明确分子量：12.2 kDa（单体），实际为二聚体形式
• 严格质量控制：提供详细的序列信息和蛋白标识（UniProt ID: Q9UK05）

产品信息

属性	描述
表达宿主	大肠杆菌
蛋白序列	人GDF2 (Ser320-Arg429) 氨基酸序列，含N端S标签
蛋白长度	110个氨基酸
活性	Testing in progress
产品形式	冻干粉（冻干缓冲液：20 mM Tris, 150 mM NaCl, pH 8.0）

生物背景

GDF-2（生长分化因子2），也称为BMP-9，是TGF-β细胞因子家族的重要成员。它在肝脏非实质细胞中高表达，并通过ALK1受体介导信号传导，参与调控肝脏网状内皮系统、葡萄糖稳态、铁稳态及血管生成抑制等生理过程。

使用说明

• 复溶建议：推荐使用配套复溶缓冲液，浓度不低于100 µg/mL
• 注意事项：使用前请离心，避免反复冻融
• 实验应用：适用于细胞培养研究，具体浓度需根据实验体系优化

保存与运输

• 保存条件：冻干粉-20°C保存1年；复溶后2-8°C可保存1周
• 长期保存：建议用含载体蛋白的缓冲液（如0.1% HSA/BSA）稀释后分装保存于-20°C或-80°C
• 运输条件：冰袋运输（蓝冰）

规格与价格

规格	价格（元）	货期
5 µg	588	现货（次日发货）
10 µg	1498	现货（次日发货）
100 µg	8869	现货（次日发货）
1 mg	请咨询	请咨询

警告：本品仅供研究使用，不适用于人类或临床诊断。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Recombinant Human Bone Morphogenetic Protein 9 (BMP-9/GDF2) Cytokine

Item No.: PRP1221

Full English Name: Human BMP-9/GDF2 protein, S tag

Product Overview

This product is a high-purity recombinant human GDF2 protein, produced via an Escherichia coli expression system with an N-terminal S tag. It is an important cytokine belonging to the TGF-β superfamily. Supplied as a lyophilized powder, it exhibits low endotoxin levels and is suitable for cell culture and related in vitro studies.

Key Features

• High purity: SDS-PAGE validated, purity > 96%
• Low endotoxin: LAL assay, endotoxin < 1 EU per µg protein
• Defined molecular weight: 12.2 kDa (monomer), exists as a dimer
• Stringent quality control: detailed sequence information and protein identification provided (UniProt ID: Q9UK05)

Product Information

Attribute	Description
Expression host	Escherichia coli
Protein sequence	Human GDF2 (Ser320-Arg429) amino-acid sequence, containing N-terminal S tag
Protein length	110 amino acids
Activity	Testing in progress
Product form	Lyophilized powder (reconstitution buffer: 20 mM Tris, 150 mM NaCl, pH 8.0)

Biological Background

GDF-2 (Growth/Differentiation Factor 2), also known as BMP-9, is a prominent member of the TGF-β cytokine family. It is highly expressed in non-parenchymal liver cells and signals through the ALK1 receptor, participating in the regulation of hepatic sinusoidal endothelial systems, glucose homeostasis, iron homeostasis, and anti-angiogenic processes.

Usage Instructions

• Reconstitution recommendation: Use the supplied reconstitution buffer; final concentration ≥ 100 µg/mL
• Precautions: Centrifuge before use and avoid repeated freeze-thaw cycles
• Experimental applications: Suitable for cell-culture studies; optimal concentration should be empirically determined for each assay

Storage and Shipping

• Storage conditions: Lyophilized powder – store at −20 °C for up to 1 year; reconstituted – store at 2‑8 °C for up to 1 week
• Long-term storage: Dilute in a carrier-protein buffer (e.g., 0.1% HSA/BSA) and aliquot for storage at −20 °C or −80 °C
• Shipping conditions: Ice-pack (dry ice) transport

Specifications and Pricing

Specification	Price (CNY)	Lead time
5 µg	588	In stock (next-day shipment)
10 µg	1498	In stock (next-day shipment)
100 µg	8869	In stock (next-day shipment)
1 mg	Please inquire	Please inquire

Warning: This product is for research use only and is not intended for human or clinical diagnostic applications.

Note: The information above may change due to product optimization or upgrades; please contact Yakoin Inc. for the most current details.