BMP-3细胞因子,重组人骨形态发生蛋白3,重组蛋白,E.c

Human BMP‑3 (重组人骨形态发生蛋白 3) – 研究级细胞因子

产品概览

• 产品名称：BMP‑3细胞因子，重组人骨形态发生蛋白 3（E.coli 表达）
• 英文名称：Human BMP‑3 Protein
• 货号：PRP1047
• 分子量：约 12.5 kDa（111 氨基酸）
• 来源物种：人（基因 ID 651）
• 表达宿主：大肠杆菌（E.coli）
• 纯度：> 95 %（SDS‑PAGE 检测）
• 标签：无标签
• 活性：Null（用于信号通路研究）

核心技术参数

项目	描述
氨基酸序列	来源于人源 BMP‑3 (Gln363‑Arg472)（UniProt P12645）
冻干缓冲液	无菌 50 mM Glycine, 150 mM NaCl, pH 3.0
LAL 检测	每 1 µg 蛋白质中的 EU 含量 < 1.0
检测指标	BMP‑3

应用概述

本产品属于细胞因子核心产品，主要面向细胞培养及信号通路研究：

• 探索 BMP‑3 在成骨抑制、软骨发育及骨重塑中的作用机制。
• 用于 TGF‑β 超家族成员的相互作用及下游 Smad 信号通路的功能验证。
• 辅助构建骨代谢、骨质疏松、骨折愈合及软骨再生等模型。

使用指南

1. 使用本产品配套的 Reconstitution Buffer（50 mM Glycine / 150 mM NaCl, pH 3.0）进行复溶，确保最终浓度不低于 100 µg/mL。
2. 复溶后建议于 4 °C 保存 2–7 天；长期保存请立刻回冷冻至 -20 °C 以下。
3. 为降低吸附并延长活性，可在复溶液中加入 0.1 % HSA 或 BSA。
4. 使用前请先离心除去可能的沉淀。
5. 如需进一步稀释，请根据实验体系的最终浓度需求采用无菌 PBS 或对应培养基进行稀释。

存储与运输

• 冻干粉储存：‑20 °C 以下、干燥环境。
• 复溶后保存：4 °C（短期 2–7 天）或‑20 °C（长期），建议分装以避免反复冻融。
• 运输条件：常温（请确保包装完整防潮防震）。

规格与采购信息

规格	单价（人民币）	库存状态
10 µg	588 元	现货（次日发货）
50 µg	1,998 元	现货（次日发货）
500 µg	9,998 元	请咨询

重要提示

本产品仅限科研使用，严禁用于人类临床诊断或治疗。使用本产品时，请确保不侵犯任何专利或许可证。对因使用本产品而产生的专利侵权或其他违规行为，本公司概不负责。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Human BMP‑3 (Recombinant Human Bone Morphogenetic Protein 3) – Research Grade Cytokine

Product Overview

• Product Name: BMP‑3 Cytokine, Recombinant Human Bone Morphogenetic Protein 3 (E.coli expressed)
• English Name: Human BMP‑3 Protein
• Catalog Number: PRP1047
• Molecular Weight: Approximately 12.5 kDa (111 amino acids)
• Source Species: Human (Gene ID 651)
• Expression Host: Escherichia coli (E.coli)
• Purity: > 95 % (as determined by SDS‑PAGE)
• Tag: Tag-free
• Activity: Null (for signaling pathway research)

Core Technical Parameters

Item	Description
Amino Acid Sequence	Derived from human BMP‑3 (Gln363‑Arg472) (UniProt P12645)
Lyophilization Buffer	Sterile 50 mM Glycine, 150 mM NaCl, pH 3.0
LAL Test	< 1.0 EU per 1 µg of protein
Detection Target	BMP‑3

Application Overview

This product is a core cytokine product, primarily intended for cell culture and signaling pathway research:

• Investigate the mechanism of BMP‑3 in osteogenesis inhibition, cartilage development, and bone remodeling.
• Used for functional validation of interactions among TGF‑β superfamily members and downstream Smad signaling pathways.
• Aid in the construction of models for bone metabolism, osteoporosis, fracture healing, and cartilage regeneration.

Usage Guide

1. Reconstitute using the provided Reconstitution Buffer (50 mM Glycine / 150 mM NaCl, pH 3.0), ensuring a final concentration not less than 100 µg/mL.
2. After reconstitution, it is recommended to store at 4 °C for 2–7 days; for long-term storage, immediately return to freezing at -20 °C or below.
3. To reduce adsorption and prolong activity, 0.1 % HSA or BSA can be added to the reconstitution solution.
4. Before use, centrifuge to remove any potential precipitate.
5. If further dilution is required, use sterile PBS or the corresponding culture medium according to the final concentration requirements of the experimental system.

Storage and Shipping

• Lyophilized Powder Storage: Below ‑20 °C, in a dry environment.
• Storage After Reconstitution: 4 °C (short-term, 2–7 days) or ‑20 °C (long-term), aliquoting is recommended to avoid repeated freeze-thaw cycles.
• Shipping Conditions: Ambient temperature (ensure packaging is intact, moisture-proof, and shock-proof).

Specifications and Purchasing Information

Specification	Unit Price (RMB)	Stock Status
10 µg	588 yuan	In stock (ships next day)
50 µg	1,998 yuan	In stock (ships next day)
500 µg	9,998 yuan	Please inquire

Important Notes

This product is intended for research use only. It is strictly prohibited for human clinical diagnosis or treatment. When using this product, ensure that it does not infringe upon any patents or licenses. The company assumes no responsibility for patent infringement or other violations arising from the use of this product.

Note: The above information is subject to change due to factors such as product optimization and upgrades. For specific details, please consult Yakeyin Company.