CXCL3细胞因子,重组人CXC趋化因子配体3,重组蛋白,E

产品详情

产品名称：重组人CXCL3细胞因子（His标签，无动物源）

英文名称：Human CXCL3 Protein, His tag (Animal-Free)

货号：PRP1006

产品分类：核心产品 - 细胞因子及蛋白

产品类型：重组蛋白

技术参数

来源种属：人源

氨基酸序列：人源CXCL3 (Ala35-Asn107) (UniProt ID: P19876)

表达宿主：大肠杆菌表达系统

分子量：8.67 kDa

蛋白长度：73个氨基酸

纯度：> 98% (SDS-PAGE检测)

标签：C端His标签

内毒素水平：< 0.1 EU/μg (LAL法测定)

生物活性

经功能活性验证，本品能够特异性趋化BaF3细胞（转染人CXCR2受体），其半数有效浓度(ED₅₀) < 2 ng/mL。

产品形态与复溶建议

产品形式：冻干粉

冻干缓冲液：无菌PBS，pH 7.4

复溶建议：推荐使用配套复溶缓冲液进行复溶，初始浓度不低于100 µg/mL。用户可根据具体实验需求，使用含载体蛋白（如0.1% BSA、10% FBS、5% HSA）或稳定剂（如5%海藻糖）的缓冲液进行进一步稀释。

保存与运输

保存条件：冻干粉可在-20°C下稳定保存1年；复溶后于2-8°C可保存1周；稀释后分装保存于-20°C或-80°C，可稳定3-6个月，请避免反复冻融。

运输条件：蓝冰低温运输

背景信息

CXCL3（C-X-C motif chemokine 3），也称为生长调节致癌基因γ（GROγ），属于CXC趋化因子家族成员。该蛋白由73个氨基酸组成，分子量约8 kDa。在炎症反应中，CXCL3可被TNF和IL-1激活，通过结合CXCR2受体介导单核细胞的迁移与黏附，并激活JNK信号通路参与细胞分化过程。

注意事项

• 使用前请离心处理
• 本品为研究使用，不适用于人体或临床诊断
• 请遵守相关专利与许可证要求

产品规格与价格

规格	价格 (￥)	货期
5 μg	588	现货（次日发货）
20 μg	1498	请咨询
100 μg	4469	请咨询
1 mg	请咨询	请咨询

基因ID：2921

别名：GRO-γ, MGSAγ, MIP-2β, GRO3, CXCL-3

UniProt链接：P19876

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Product Details

Product Name: Recombinant Human CXCL3 Protein (His Tag, Animal-Free)

English Name: Human CXCL3 Protein, His tag (Animal-Free)

Catalog Number: PRP1006

Product Category: Core Products - Cytokines & Proteins

Product Type: Recombinant Protein

Technical Parameters

Source Species: Human

Amino Acid Sequence: Human CXCL3 (Ala35-Asn107) (UniProt ID: P19876)

Expression Host: E. coli Expression System

Molecular Weight: 8.67 kDa

Protein Length: 73 amino acids

Purity: > 98% (as determined by SDS-PAGE)

Tag: C-terminal His Tag

Endotoxin Level: < 0.1 EU/μg (determined by LAL method)

Biological Activity

Functionally validated, this product specifically chemoattracts BaF3 cells (transfected with human CXCR2 receptor), with a half maximal effective concentration (ED₅₀) < 2 ng/mL.

Form and Reconstitution

Form: Lyophilized powder

Lyophilization Buffer: Sterile PBS, pH 7.4

Reconstitution Recommendation: It is recommended to reconstitute using the provided reconstitution buffer to an initial concentration ≥100 µg/mL. For specific experimental needs, further dilution can be performed using buffers containing carrier proteins (e.g., 0.1% BSA, 10% FBS, 5% HSA) or stabilizers (e.g., 5% trehalose).

Storage and Shipping

Storage: The lyophilized powder is stable for 1 year when stored at -20°C. After reconstitution, it is stable for 1 week at 2-8°C. Aliquot and store diluted aliquots at -20°C or -80°C for 3-6 months. Avoid repeated freeze-thaw cycles.

Shipping: Shipped on blue ice.

Background

CXCL3 (C-X-C motif chemokine 3), also known as Growth Regulated Oncogene Gamma (GROγ), is a member of the CXC chemokine family. This protein consists of 73 amino acids with an approximate molecular weight of 8 kDa. In inflammatory responses, CXCL3 can be activated by TNF and IL-1. It mediates monocyte migration and adhesion by binding to the CXCR2 receptor and participates in cell differentiation processes by activating the JNK signaling pathway.

Notice

• Centrifuge briefly before use.
• This product is for research use only and is not intended for human or diagnostic use.
• Please comply with relevant patent and licensing requirements.

Specifications & Pricing

Specification	Price (¥)	Availability
5 μg	588	In Stock (Ships Next Day)
20 μg	1498	Please Inquire
100 μg	4469	Please Inquire
1 mg	Please Inquire	Please Inquire

Gene ID: 2921

Aliases: GRO-γ, MGSAγ, MIP-2β, GRO3, CXCL-3

UniProt Link:P19876

Note: The above information is subject to change due to factors such as product optimization and upgrades. Please consult ArKayBi for specific details.