IL-6 重组大鼠白介素-6 大鼠重组蛋白 细胞因子

产品概述

重组大鼠白介素-6（Rat IL-6 Protein）是一种高纯度、无标签的重组蛋白，专为体外细胞培养与功能研究设计。该产品通过大肠杆菌表达系统合成，保留了IL-6的天然生物活性结构，适用于大鼠来源的细胞模型研究。

产品特性

• 货号：PRP1241
• 种属：大鼠（Rattus norvegicus）
• 表达宿主：大肠杆菌
• 蛋白长度：187个氨基酸，预测分子量为21.73 kDa
• 纯度：经SDS-PAGE检测，纯度 > 99%
• 内毒素水平：＜1.0 EU/μg（LAL法测定）
• 产品形式：冻干粉，缓冲体系为20 mM Tris，150 mM NaCl，pH 7.4

生物学背景

白介素-6（IL-6）是一种多功能的α-螺旋细胞因子，在免疫调节、急性期反应、造血、骨代谢及肿瘤进展中发挥关键作用。它通过与其受体IL-6R和gp130形成的异源二聚体复合物传导信号，在从先天免疫向获得性免疫的转变中具有重要作用。

使用说明

• 复溶建议：推荐使用配套的Reconstitution Buffer（10 mM HCl）进行复溶，浓度建议不低于100 μg/mL。后续可根据实验体系进一步稀释。
• 保存条件：冻干粉应在-20℃以下干燥保存。复溶后可在4℃稳定保存2–7天，长期保存需置于-20℃以下，建议添加0.1% HSA或BSA作为载体蛋白，分装避免反复冻融。
• 注意事项：使用前请离心，避免产品损失。

运输与规格

规格	价格（元）	货期
5 μg	588	现货，次日发货
20 μg	1498	现货，次日发货
100 μg	3898	现货，次日发货
1 mg	请咨询

运输方式：冰袋运输（蓝冰）

应用领域

• 大鼠细胞培养体系中的增殖与分化研究
• 免疫响应与炎症机制研究
• 信号通路分析及相关受体功能实验

注意事项

警告：本品仅供科研使用，不适用于人体或临床诊断。使用者应确保应用符合相关法律法规及知识产权要求。

别名参考：Interleukin6, IL-6, IL6, BSF2, HGF, HSF, IFNB2, CDF 等

UniProt 编号：P20607 (Rattus norvegicus)

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Product Overview

Recombinant Rat Interleukin-6 (Rat IL-6 Protein) is a high-purity, tag-free recombinant protein specifically designed for in vitro cell culture and functional studies. This product is synthesized using an E. coli expression system and retains the natural bioactive structure of IL-6, making it suitable for research involving rat-derived cell models.

Product Features

• Catalog Number: PRP1241
• Species: Rat (Rattus norvegicus)
• Expression Host: E. coli
• Protein Length: 187 amino acids, predicted molecular weight of 21.73 kDa
• Purity: > 99% as determined by SDS-PAGE
• Endotoxin Level: < 1.0 EU/μg (determined by LAL method)
• Product Form: Lyophilized powder, buffer system: 20 mM Tris, 150 mM NaCl, pH 7.4

Biological Background

Interleukin-6 (IL-6) is a multifunctional alpha-helical cytokine that plays key roles in immune regulation, acute-phase response, hematopoiesis, bone metabolism, and tumor progression. It signals through a heterodimeric complex formed with its receptor IL-6R and gp130, and is critically involved in the transition from innate to adaptive immunity.

Usage Instructions

• Reconstitution Recommendation: It is recommended to reconstitute using the provided Reconstitution Buffer (10 mM HCl) to a concentration not less than 100 μg/mL. Further dilution can be performed according to the experimental system.
• Storage Conditions: The lyophilized powder should be stored dry below -20°C. After reconstitution, it can be stored stably at 4°C for 2–7 days. For long-term storage, keep below -20°C, and it is advisable to add 0.1% HSA or BSA as a carrier protein. Aliquot to avoid repeated freeze-thaw cycles.
• Precautions: Centrifuge before use to avoid product loss.

Shipping & Specifications

Specification	Price (CNY)	Availability
5 μg	588	In stock, ships next day
20 μg	1498	In stock, ships next day
100 μg	3898	In stock, ships next day
1 mg	Please inquire

Shipping Method: Shipped with ice packs (blue ice)

Application Areas

• Proliferation and differentiation studies in rat cell culture systems
• Immune response and inflammation mechanism research
• Signal pathway analysis and related receptor function experiments

Precautions

Warning: This product is intended for research use only and is not suitable for human use or clinical diagnosis. Users must ensure that its application complies with relevant laws, regulations, and intellectual property requirements.

Alias Reference: Interleukin6, IL-6, IL6, BSF2, HGF, HSF, IFNB2, CDF, etc.

UniProt Accession: P20607 (Rattus norvegicus)

Note: The above information is subject to change due to factors such as product optimization and upgrades. For specific details, please contact Yakeyin Company.