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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD85a (ILT5)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA207
- 标记物:
VioBlue
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:11
- 抗体英文名:
CD85a (ILT5) Antibody, anti-human, REAfinity™
- 抗体名:
CD85a (ILT5) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 300 µL
Identification and enumeration of CD85a (ILT5)+ cells by flow cytometryClone REA207 recognizes the CD85a antigen, a immunoglobulin superfamily transmembrane glycoprotein also known as leukocyte immunoglobulin-like receptor member 3 (LIR-3) or immunoglobulin-like transcript 5 (ILT5). CD85a is preferentially expressed by monocytes, macrophages, dendritic cells, and granulocytes. It provides inhibitory signals through interaction with MHC class I molecules and becomes activated upon co-ligation of CD85a and immune receptors, such as CD32 and the B cell receptor. CD85a down-regulates antigen-induced B cell–activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitory motifs. | Additional information: Clone REA207 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Borges, L. et al. (1997) A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J Immunol 159: 5192–5196. | Ma, G. et al. (2011) Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells. Immunity 34 (3): 385–395. | Colonna, M. et al. (1999) Inhibitory and activating receptors involved in immune surveillance by human NK and myeloid cells. J Leukoc Biol 66: 718–722.
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CD85a (ILT5) Antibody, anti-human, VioBlue®, REAfinity™, 30 tests in 300 µL
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