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- 详细信息
- 技术资料
- 免疫原:
Ly-49G2
- 亚型:
rat IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
4D11
- 标记物:
PE
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 靶点:
Ly-49G2
- 抗体英文名:
Ly-49G2 Antibody, anti-mouse
- 抗体名:
Ly-49G2 Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Identification and enumeration of Ly-49G2+ cells by flow cytometryThe monoclonal antibody 4D11 recognizes Ly-49G2, which is a inhibitory receptor specific for class Ia MHC molecules. Ly-49G2 belongs to the Ly-49 multigene family, which consists of type II transmembrane homodimeric receptors. Inhibitory Ly-49 members such as Ly-49G2 contain immunoreceptor tyrosine-based inhibitory motif (ITIM) 3 in their cytoplasmic tail and transduce signal that prevents the NK cell cytolytic activity upon recognizing ligands such as H-2Ddk. Expression of Ly-49G2 is found on subsets of natural killer (NK) cells, NK-T cells, and on a population of memory CD8+ T cells (in C57BL/6 mice). |
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Ly-49G2 Antibody, anti-mouse, PE, 30 µg in 1 mL
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