- 询价
- Miltenyi Biotec
- 德国
- 130-131-345
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD229 (Ly-9)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA963
- 标记物：
Vio Bright V423
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD229 (Ly-9) Antibody, anti-human, REAfinity™
- 抗体名：
CD229 (Ly-9) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD229 (Ly-9)+ cells by flow cytometryClone REA963 recognizes the human CD229 antigen, a type I transmembrane glycoprotein belonging to the CD150 subfamily of leukocyte receptors of the Ig superfamily. CD229, also known as Ly-9, has four extracellular Ig domains and a cytoplasmic domain containing two copies of the tyrosine-based motif (T-I/V-Y-x-x-V/I). Via this unique motif, CD229 interacts with SH2-binding phosphatases and the adapter molecules SAP, EAT-2, and Grb2. Expression of CD229 is found on T cells, B cells, NK cells, and thymocytes. CD229 interacts homophilically via its N-terminal V-like domain and is involved in enhancing T cell activation and Tʜ2 polarization. | Additional information: Clone REA963 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Romero, X. et al. (2004) Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4). Tissue Antigens 64 (2): 132–144. | Romero, X. et al. (2005) CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J Immunol 174 (11): 7033–7042. | Martín, M. et al. (2005) Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. J Immunol 174: 5977–5986.
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CD229 (Ly-9) Antibody, anti-human, Vio® Bright V423, REAfinity™, 100 tests in 200 µL
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