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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD48
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1238
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD48 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD48 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD48+ cells by flow cytometryClone REA1238 reacts with the CD48 mouse antigen, which is a 45 kDa GPI-linked glycoprotein also known as BCM1, blast-1 (human), or OX-45 (rat). CD48 belongs to the SLAM family including CD48, CD244, and CD150. These cell surface receptors were differentially expressed among functionally progenitors. Hematopoietic stem cells are highly purified as CD150–CD48–CD244– cells, multipotent hematopoietic progenitors are CD244+CD150–CD48– and most restricted progenitor cells are CD48+CD244+CD150–. In mouse, the ligands for CD48 are CD2 and CD244. | Additional information: Clone REA1238 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Latchman, Y. et al. (1998) Cutting edge: Identification of the 2B4 molecule as a counter-receptor for CD48. J Immunol 161: 5809–5812. | Kato, K. et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J. Exp. Med. 176: 1241. | Kiel, M. J. et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121 (7): 1109–1121.
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CD48 Antibody, anti-mouse, APC, REAfinity™, 30 µg in 200 µL
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