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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD45RC
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1271
- 标记物:
Vio Bright B515
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD45RC Antibody, anti-human, REAfinity™
- 抗体名:
CD45RC Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD45RC+ cells by flow cytometryClone REA1271 recognizes the CD45RC isoforms of the human CD45 antigen, a member of the protein tyrosine phosphatase (PTP) family, also known as the leukocyte common antigen (LCA). The CD45 molecule is a type I transmembrane protein which is required for T and B cell activation and involved in cell growth, differentiation, mitotic cycle, and oncogenic transformation. | CD45RC is expressed on medullary thymocytes, CD8+ T cells, B cells, NK cells, and by subsets of cortical thymocytes or CD4+ T cells and involded in regulating receptor-mediated leucocyte signaling responses. | Additional information: Clone REA1271 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Zapata, J. M. et al. (1994) Human CD45RC specificity. A novel marker for T cells at different maturation and activation stages. J Immunol 152 (8): 3852–3861. | Poppema, S. et al. (1996) CD45 (leucocyte common antigen) expression in T and B lymphocyte subsets. Leuk. Lymphoma 20 (3-4): 217–222.
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CD45RC Antibody, anti-human, Vio® Bright B515, REAfinity™, 100 tests in 200 µL
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