- 询价
- Miltenyi Biotec
- 德国
- 130-108-075
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
C3a Receptor
- 亚型：
mouse IgG2b
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
hC3aRZ8
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
mouse
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:11
- 靶点：
C3a Receptor
- 抗体英文名：
C3a Receptor Antibody, anti-human
- 抗体名：
C3a Receptor Antibody, anti-human
- 规格：
100 tests in 1 mL
Identification and enumeration of C3a receptor+ cells by flow cytometryClone hC3aRZ8 recognizes the human C3a anaphylatoxin chemotactic receptor (C3aR) antigen, a 54 kDa seven transmembrane GTP-binding-protein–coupled receptor which belongs to the rhodopsin supergene family. C3aR is expressed by various cells, including cells of hematopoietic origin such as neutrophils and monocytes, but also non-hematopoietic cells such as renal proximal tubular epithelial cells or neural cells. C3aR functions as a cell surface receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, a C-terminal 77 amino acid cleavage product of the alpha chain of C3. All cellular responses to C3a are specifically mediated by interactions with the membrane bound C3aR. After C3a binding, the C3aR signaling results in chemotaxis, granule enzyme release, and superoxide anion production. C3aR binding on T cells promotes CD4+ and CD8+ T cell activation, proliferation, differentiation, and survival, independently of TCR signals. |
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C3a Receptor Antibody, anti-human, APC, 100 tests in 1 mL
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