- 询价
- Miltenyi Biotec
- 德国
- 130-116-921
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD275 (B7-H2)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA991
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD275 (B7-H2) Antibody, anti-human, REAfinity™
- 抗体名：
CD275 (B7-H2) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD275 (B7-H2)+ cells by flow cytometryClone REA991 recognizes the human CD275 antigen, also known as B7-H2, ICOSL, or GL50, a member of the B7 family of co-stimulatory molecules involved in regulating T cell activation and effector functions. It belongs to the Ig superfamily and has a predicted molecular weight of 40 kDa. CD275 is a ligand of inducible co-stimulator (ICOS) expressed on activated T cells. ICOS mediated co-stimulation promotes T helper (Tʜ) cell differentiation via Tʜ2 cytokine production such as interleukin 10 (IL-10) and IL-4. Human CD275 is expressed on B cells, dendritic cells, endothelial cells, renal tubular epithelial cells, activated monocytes, and human airway epithelial cells. | Additional information: Clone REA991 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Wang, S. et al. (2000) Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood 96 (8): 2808–2813. | Qian, X. et al. (2006) The ICOS-ligand B7-H2, expessed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system. Eur. J. Immunol. 36 (4): 906–918. | Kurosawa, S. et al. (2003) Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 28: 563–573.
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CD275 (B7-H2) Antibody, anti-human, FITC, REAfinity™, 30 tests in 60 µL
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