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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
FOLR1
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1336
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
FOLR1 Antibody, anti-human, REAfinity™
- 抗体名:
FOLR1 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of FOLR1+ cells by flow cytometryClone REA1336 recognizes the human cell surface glycoprotein FOLR1, also known as Folate receptor alpha or Adult folate-binding protein. FOLR1 belongs to the folate receptor family and expression is mainly found in tissues of epithelial origin, including placenta and thymus epithelium, kidney, lung and cerebellum. Expression is increased in malignant tissues. FOLR1 binds folic acid and its reduced derivatives and transport 5-methyltetrahydrofolate into cells. | REA1336 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Kelemen, L. E. The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander? Int. J. Cancer 119 (2): 243–250. | Cheung, A. et al. (2016) Targeting folate receptor alpha for cancer treatment. Oncotarget. 9 (32): 52553–52574. | Shivange, G. et al. (2018) A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer. Cancer Cell 34 (2): 331 dou–345.
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FOLR1 Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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