CD206 (MMR) Antibody, anti-human/mouse, PE, REAfinity™, 200 µL
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CD206 (MMR) Antibody, anti-hum

an/mouse, PE, REAfinity™, 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-137-717
  • 2025年12月09日
  • MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • human cell line
  • human, mouse
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD206 (MMR)

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA1447

    • 标记物

      PE

    • 适应物种

      human, mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 抗体英文名

      CD206 (MMR) Antibody, anti-human/mouse, REAfinity™

    • 抗体名

      CD206 (MMR) Antibody, anti-human/mouse, REAfinity™

    • 规格

      200 µL

    Recombinant antibody for the detection of CD206 (MMR)+ cellsClone REA1447 recognizes the CD206 (MMR), the macrophage mannose receptor (MMR).. CD206 is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. CD206 recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. CD206 mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. |

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    图标文献和实验
    该产品被引用文献
    Wileman, T. E. et al. (1986) Identification of the macrophage mannose receptor as a 175-kDa membrane protein. Proc. Natl. Acad. Sci. U.S.A. 83: 2501–2505. | Lennartz, M. R. et al. (1989) Biosynthesis and processing of the mannose receptor in human macrophages. J. Biol. Chem. 264: 2385–2390. | Ezekowitz, R. A. B. et al. (1990) Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cells. J. Exp. Med. 172: 1785–1794. | Sallusto, F. et al. (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartement: downregulation by cytokines and bacterial products.​ J. Exp. Med. 182: 389–400. | Feinberg, H. et al. (2000) Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor. J. Biol. Chem. 275: 21539–21548. | Kang, P. B. et al. (2005) The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. J. Exp. Med. 202: 987–999. | Tacken, P. J. et al. (2005) Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood 106: 1278–1285. | Ng, Y. S. (2012) Chemical transfection of dye-conjugated microRNA precursors for microRNA functional analysis of M2 macrophages. J. Cell. Biochem. 113 (5): 1714–1723.
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    文献支持
    CD206 (MMR) Antibody, anti-human/mouse, PE, REAfinity™, 200 µL
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