产品封面图
文献支持

CD170 (Siglec-5) Antibody, ant

i-human, pure, REAfinity™, 100 µg in 100 µL
收藏
  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-126-463
  • 2025年12月09日
  • Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
  • human cell line
  • human, non-human primate
avatar
德国美天旎生物技术有限公司
品牌商
14 年钻石会员

  • 企业认证

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      CD170 (Siglec-5)

    • 亚型：

      recombinant human IgG1

    • 形态：

      Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.

    • 保存条件：

      避光，4-8℃

    • 克隆性：

      REA1077

    • 标记物：

      pure

    • 适应物种：

      human, non-human primate

    • 保质期：

      24个月

    • 供应商：

      Miltenyi Biotec

    • 宿主：

      human cell line

    • 应用范围：

      Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry

    • 浓度：

      1:50

    • 抗体英文名：

      CD170 (Siglec-5) Antibody, anti-human, REAfinity™

    • 抗体名：

      CD170 (Siglec-5) Antibody, anti-human, REAfinity™

    • 规格：

      100 µg in 100 µL

    Identification and enumeration of CD170 (Siglec-5)+ cells by mass cytometryClone REA1077 recognizes the CD170 antigen, a single-pass transmembrane protein member of the immunoglobulin superfamily, also known as sialic acid-binding Ig-like lectin 5 (Siglec-5). CD170 is expressed on neutrophils, monocytes, dendritic cells, and subsets of tissue macrophages. It contains two tyrosine-based motifs in its cytoplasmic tail implicating signaling functions and forms a 140 kDa dimer on the cell surface. Tyrosine phosphorylation of CD170 leads to recruitment of the tyrosine phosphatases SHP-1 and SHP-2, which in turn efficiently inhibits FcεRI-mediated calcium fluxing and serotonin release. CD170 binds α 2-3- and α 2-6-linked sialic acid as well as glycophorin A, and is involved in cell adhesion. | Additional information: Clone REA1077 displays negligible binding to Fc receptors.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献
    Cornish, A. L. et al. (1998) Characterization of Siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33. Blood 92 (6): 2123–2132. | Erickson-Miller, C. L. et al. (2003) Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes. Exp. Hematol. 31 (5): 382–388. | Avril, T. et al. (2005) Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation. J. Biol. Chem. 280: 19843–19851.
    相关实验

    • 用 CD3/CD28 做好 T 细胞激活与扩增

      7211011 小鼠淋巴细胞分离液 达优 100339 Ultra-LEAF™ Purified anti-mouse CD3ε Antibody BioLegend 102115 Ultra-LEAF™ Purified anti-mouse CD28 Antibody BioLegend   CD3/CD28 Streptamer® 多聚体法：   货号 名称

    • RNA-biotin based pulldown assays for the detection of siRNA targeted genomic regions and siRNA directed histone modifications (PROT32)

      in 100µl of elution buffer at 65°C for 5 minutes;7.The eluted complexes can then be electrophoresed in denaturing PAGE and subjected to western blot analysis with an anti-Flag antibody for detection of the particular flag-tagged protein of choice (Figure

    • 用全血直接分选 CD3+ T 细胞

      × Buffer CI 稀释至 1×； 1.2 用 1 ml Buffer CI 溶解冻干粉的 Fab-Strep，用移液器反复吹打，不能涡旋！溶解后的 Fab-Strep 进行分装保存（可 200µl 每管），冻存于- 20°C，避免反复冻融； 1.3 往 200µl 溶解后的 Fab-Strep 中，加入 800µl 的 Buffer CI 。此时，Fab-Strep 溶液已准备好，可直接使用了； 1.4 加入 200µl 100 mM 的生物素至 20 ml Buffer CI 中，混匀

    查看更多相关实验 >
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Podoplanin Antibody, anti-human, pure, REAfinity™, 100 µg in 100 µL
    询价
    德国美天旎生物技术有限公司
    2025年12月09日询价
    Human IDO 100 µg
    ￥3475.48
    北京博蕾德生物科技有限公司
    2025年05月16日询价
    APC anti-human CD170 (Siglec-5)
    ￥500
    北京百奥创新科技有限公司
    2025年07月14日询价
    SPY | Spindly (100 µg)
    询价
    Agrisera AB
    2025年11月23日询价
    SPY|Spindly (100 µg)
    ￥3107
    上海经科化学科技有限公司
    2025年07月27日询价
    文献支持
    CD170 (Siglec-5) Antibody, anti-human, pure, REAfinity™, 100 µg in 100 µL
    询价