- 询价
- Miltenyi Biotec
- 德国
- 130-106-872
- 2025年12月09日
- Flow cytometry, Immunocytochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TRA-1-60
- 亚型：
recombinant human IgG1
- 形态：
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件：
避光，2-8℃
- 克隆性：
REA157
- 标记物：
Vio 488
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, Immunocytochemistry
- 抗体英文名：
TRA-1-60 Antibody, anti-human, REAfinity™
- 抗体名：
TRA-1-60 Antibody, anti-human, REAfinity™
- 规格：
100 µL
Detection of TRA-1-60+ cells in cell cultureClone REA157 recognizes the TRA-1-60 antigen, a neuraminidase-resistant carbohydrate epitope expressed on podocalyxin, which is a transmembrane glycoprotein. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and tumor marker. TRA-1-60 antigen is expressed on the surface of human embryonic stem cells (ESC), embryonic germ cells (EG), and embryonic carcinoma cells (EC). Expression of TRA-1-60 is lost upon differentiation and thus it can be used to assess the differentiation stage of the cells. TRA-1-60 can be detected in the serum of patients with germ cell tumors which contain an EC component. | Additional information: Clone REA157 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Andrews, P. W. et al. (1984) Three monoclonal antibodies defining distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells. Hybridoma 3 (4): 347–361. | Lajer, H. et al. (2002) Clinical use of serum TRA-1-60 as tumor marker in patients with germ cell cancer. Int. J. Cancer 100 (2): 244–246. | Schopperle, W. M. et al. (2007) The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma. Stem Cells 25 (3): 723–730.
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TRA-1-60 Antibody, anti-human, Vio® 488, REAfinity™, 100 µL
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