- 询价
- Miltenyi Biotec
- 德国
- 130-111-219
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Integrin β5
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA718
- 标记物：
Vio Bright FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
Integrin β5 Antibody, anti-human, REAfinity™
- 抗体名：
Integrin β5 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of integrin β5+ cells by flow cytometryClone REA718 recognizes the human integrin β5 antigen, a 95 kDa glycoprotein single-pass type I membrane protein. Integrins are a family of transmembrane receptors that mediate adhesion of cells to extracellular matrices, as well as intercellular interactions. These interactions transduce signals that control complex cell functions such as proliferation, differentiation, and survival, and require the regulation of gene expression. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. The integrin αV/β5 heterodimer is found on many types of tissue cells, such as epithelial cells, endothelial cells, keratinocytes, and osteoblastic cells. It is a receptor for fibronectin and vitronectin and acts as a receptor for adenovirus type C. | Additional information: Clone REA718 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Kim, J. P. et al. (1994) Vitronectin-driven human keratinocyte locomotion is mediated by the alpha v beta 5 integrin receptor. J. Biol. Chem. 269 (43): 26926–26932. | Zhang, H. et al. (2004) Myosin-X provides a motor-based link between integrins and the cytoskeleton. Nat. Cell Biol. 2004 (6): 523–531. | Lyle, C. et al. (2010) Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells. J. Virol. 7 (148): 1743–1745.
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Integrin β5 Antibody, anti-human, Vio® Bright FITC, REAfinity™, 100 tests in 200 µL
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