CD94 Antibody, anti-mouse, PE-Vio® 615, REAfinity™, 150 µg in 1 mL
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CD94 Antibody, anti-mouse, PE-

Vio® 615, REAfinity™, 150 µg in 1 mL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-122-054
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD94

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA1186

    • 标记物

      PE-Vio 615

    • 适应物种

      mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      CD94 Antibody, anti-mouse, REAfinity™

    • 抗体名

      CD94 Antibody, anti-mouse, REAfinity™

    • 规格

      150 µg in 1 mL

    Identification and enumeration of CD94+ cells by flow cytometryClone REA1186 recognizes the murine CD94 antigen, an approximately 70 kDa single-pass type II transmembrane protein, which belongs to C-type lectin superfamily. CD94 associates covalently with NKG2 family members and forms disulfide bonded heterodimers. CD94-NKG2 receptors bind HLA-E, the nonclassical MHC class Ib molecule. Depending on the associated NKG2 member, CD94-NKG2 heterodimer transmits either activating or inhibitory signal. For e.g via immunoreceptor tyrosine based-inhibitory motifs (ITIMs) containing NKG2A, CD94-NKG2A heterodimers inhibit NK cell cytotoxicity. Besides NK cells, expression of CD94-NKG2 heterodimers is also shown on NK-T cells and a small percentage of CD8+ cells in most mouse strains. DBA/2J mice do not express CD94. | Additional information: Clone REA1186 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Vance, R. E. et al. (1997) Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells. Eur. J. Immunol. 27 (12): 3236–3241. | Ho, E. L. et al. (1998) Murine Nkg2d and CD94 are clustered within the natural killer complex and are expressed independently in natural killer cells. Proc. Natl. Acad. Sci. U.S.A. 95 (11): 6320–6325.
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    CD94 Antibody, anti-mouse, PE-Vio® 615, REAfinity™, 150 µg in 1 mL
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