- 询价
- Miltenyi Biotec
- 德国
- 130-127-970
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TCRβ
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA318
- 标记物：
PE-Vio 770
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
TCRβ Antibody, anti-mouse, REAfinity™
- 抗体名：
TCRβ Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of TCRβ+ cells by flow cytometryClone REA318 recognizes the mouse T cell receptor beta chain (TCRβ). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCRβ is expressed on TCRα/β T cells and thymocytes, NK1.1+ thymocytes and NK-T cells. | Additional information: Clone REA318 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Robins, H. S. et al. (2009) Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells. Blood 114 (19): 4099–4107. | Schumm, M. et al. (2013) Depletion of T-cell receptor alpha/beta and CD19 positive cells from apheresis products with the CliniMACS device. Cytotherapy 15 (10): 1253–1258. | Okuno, Y. et al. (2013) CD8+ CD122+ regulatory T cells contain clonally expanded cells with identical CDR3 sequences of the T-cell receptor β-chain. Immunology 139 (3): 309–317.
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文献支持
TCRβ Antibody, anti-mouse, PE-Vio® 770, REAfinity™, 30 µg in 200 µL
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